PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga

Family

Trihelix

Protein Properties

Length: 348aa MW: 38369.3 Da PI: 9.9322

Description

Trihelix family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PSME_00029789-RA	genome	PRS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	trihelix	65.9	8.4e-21	65	128	1	64
trihelix 1 rWtkqevlaLiearremeerlrrgklkkplWeevskkmrergferspkqCkekwenlnkrykki 64 +W +e+++ i++r e+e+++ ++k++k+lWe +s++m+e+gf+rs+kqCk+kw+n +ryk++ PSME_00029789-RA 65 QWGFKETKEFIAIRAELEKDFTQTKRNKTLWELISSRMKEKGFRRSSKQCKCKWKNFVNRYKAC 128 69************************************************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd12203	9.66E-30	64	126	No hit	No description
Pfam	PF13837	9.0E-16	65	128	No hit	No description
PROSITE profile	PS50090	6.969	66	122	IPR017877	Myb-like domain
SuperFamily	SSF47794	6.08E-7	124	167	IPR010995	DNA repair Rad51/transcription factor NusA, alpha-helical
Gene3D	G3DSA:1.10.150.20	5.3E-12	125	166	No hit	No description
Pfam	PF08423	1.5E-60	166	346	IPR013632	DNA recombination and repair protein Rad51, C-terminal
SuperFamily	SSF52540	4.09E-24	166	346	IPR027417	P-loop containing nucleoside triphosphate hydrolase
CDD	cd01123	5.46E-61	166	346	No hit	No description
Gene3D	G3DSA:3.40.50.300	6.0E-43	167	346	IPR027417	P-loop containing nucleoside triphosphate hydrolase
PROSITE profile	PS50162	13.75	172	315	IPR020588	DNA recombination and repair protein RecA-like, ATP-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006281	Biological Process	DNA repair
GO:0003677	Molecular Function	DNA binding
GO:0005524	Molecular Function	ATP binding
GO:0008094	Molecular Function	DNA-dependent ATPase activity

Sequence ? help Back to Top
Protein Sequence Length: 348 aa Download sequence Send to blast
MMMGGGGEVE GMGLGVMAAL PLQLTPTVAI SSGNHLGGSN NSSLLTNSGG GGLNNNLKKD 60 DMIPQWGFKE TKEFIAIRAE LEKDFTQTKR NKTLWELISS RMKEKGFRRS SKQCKCKWKN 120 FVNRYKACGI SVVDIKKLKD VGHCMVEAVA YSPKKKLVQI KGLSDAKLPL DQGGGQGKAL 180 YIDAEGTFRP QRLLQIAERY EELFTFGFER LNSQTFNILR SCRFGLNGVD VLENVAYAKA 240 YNTDHQSRLL LEAASMMAET RFALMIVDSA TSLYRTDFVG RGELSAWQMH LAKFLRSIQK 300 MADEFGVEVV VTNQVVAQVD GSTMFAGPQV KPIGGNIIAH ASTTRFGK

Sequence ? help Back to Top

Protein Sequence Length: 348 aa Download sequence Send to blast

MMMGGGGEVE GMGLGVMAAL PLQLTPTVAI SSGNHLGGSN NSSLLTNSGG GGLNNNLKKD  60
DMIPQWGFKE TKEFIAIRAE LEKDFTQTKR NKTLWELISS RMKEKGFRRS SKQCKCKWKN  120
FVNRYKACGI SVVDIKKLKD VGHCMVEAVA YSPKKKLVQI KGLSDAKLPL DQGGGQGKAL  180
YIDAEGTFRP QRLLQIAERY EELFTFGFER LNSQTFNILR SCRFGLNGVD VLENVAYAKA  240
YNTDHQSRLL LEAASMMAET RFALMIVDSA TSLYRTDFVG RGELSAWQMH LAKFLRSIQK  300
MADEFGVEVV VTNQVVAQVD GSTMFAGPQV KPIGGNIIAH ASTTRFGK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1n0w_A	3e-76	167	346	49	204	DNA repair protein RAD51 homolog 1
5np7_C	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5np7_D	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5np7_E	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5np7_F	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5np7_G	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_A	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_B	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_C	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_D	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_E	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_F	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_G	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_H	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_I	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_J	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_K	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_L	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_M	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
5nwl_N	3e-75	167	346	145	300	DNA repair protein RAD51 homolog 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA (By similarity). Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination. {ECO:0000250, ECO:0000269\|PubMed:10330467, ECO:0000269\|PubMed:12897254}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT118588	1e-165	BT118588.1 Picea glauca clone GQ04008_A03 mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012447907.1	1e-102	PREDICTED: DNA repair protein RAD51 homolog isoform X4
Swissprot	Q9XED7	4e-92	R51A2_MAIZE; DNA repair protein RAD51 homolog B
TrEMBL	A0A1U8JN72	6e-98	A0A1U8JN72_GOSHI; DNA repair protein RAD51 homolog isoform X3
STRING	Lus10039928	2e-99	(Linum usitatissimum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G01380.1	4e-25	Trihelix family protein

Publications ? help Back to Top
Franklin AE, et al. Three-dimensional microscopy of the Rad51 recombination protein during meiotic prophase. Plant Cell, 1999. 11(5): p. 809-24 [PMID:10330467] Franklin AE,Golubovskaya IN,Bass HW,Cande WZ Improper chromosome synapsis is associated with elongated RAD51 structures in the maize desynaptic2 mutant. Chromosoma, 2003. 112(1): p. 17-25 [PMID:12811575] Pawlowski WP,Golubovskaya IN,Cande WZ Altered nuclear distribution of recombination protein RAD51 in maize mutants suggests the involvement of RAD51 in meiotic homology recognition. Plant Cell, 2003. 15(8): p. 1807-16 [PMID:12897254]