PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK29179.1
Organism
Cannabis sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family bHLH
Protein Properties Length: 624aa    MW: 69486.9 Da    PI: 6.4643
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK29179.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.45.2e-13455501455
                HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  PK29179.1 455 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 501
                799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142154.4E-5653241IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474593.01E-18450514IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.047451500IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.26E-14454505No hitNo description
Gene3DG3DSA:4.10.280.106.3E-18455514IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.9E-10455501IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.8E-16457506IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 624 aa     Download sequence    Send to blast
MKSEVGFGGS GVWNDEDKAM VEAVLGTRAF DYLISSSVTN ENLLMAIGSD ENLQNKLSDL  60
VERPNASNFS WNYAIFWQIS RSKSGDWVLG WGDGSCREPR EGEESEATRI LNLRHEDETQ  120
QRMRKRVLQK LHNLFGGSDE DNYALGLDRV TDTEIFFLAS MYFSFPRGEG GPGKCYASGK  180
HLWLLDALKS SSDYCVRSFL AKSAGIQTIV LVPTEVGVVE LGSVRSVGES LELLQSLRSL  240
FSTQSSLTRV GKPIAVLPLM VDKRDENVNL TNSGILERNE SVGVHKIFGQ DLNAGTVARP  300
HYREKLAIRK LEERPWDLYP NGNGNRIAFS GPRNGVHGST WPHSLQVQGV KQQGNPTEIY  360
ASQCPKSTNI QEIVNGVRED FRLNNYQPQK QQVQMQIDFS GATSRSSNHR PASAESEHSD  420
VEPSCKEERP STAADERRPR KRGRKPANGR EEPLNHVEAE RQRREKLNQR FYALRAVVPN  480
ISKMDKASLL GDAIAYINEL QAKLKVMETE REKVGSCSTA AAMEANNPDM EIQSRVPDVD  540
VKVVNDEVIV RVSCHLESHP ASRVIQAFNE AQISVVDSKF TTVNDTVFHD FVIKSQGSEQ  600
LTKEKLIAAF SIEANSLQTL SSVG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A5e-30449514265Transcription factor MYC2
5gnj_B5e-30449514265Transcription factor MYC2
5gnj_E5e-30449514265Transcription factor MYC2
5gnj_F5e-30449514265Transcription factor MYC2
5gnj_G5e-30449514265Transcription factor MYC2
5gnj_I5e-30449514265Transcription factor MYC2
5gnj_M5e-30449514265Transcription factor MYC2
5gnj_N5e-30449514265Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1436444RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024024130.10.0LOW QUALITY PROTEIN: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A2P5FHN30.0A0A2P5FHN3_TREOI; Basic helix-loop-helix transcription factor
STRINGXP_010100724.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]