PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

bHLH

Protein Properties

Length: 310aa MW: 34621.6 Da PI: 8.7481

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK10562.2	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	57.4	2.5e-18	238	287	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h++ E+rRR++iN++f++Lrel+P+ ++K +Ka+ L +++eYI++Lq PK10562.2 238 RSKHSATEQRRRSKINDRFQRLRELIPNI----DQKRDKASFLLEVIEYIQYLQ 287 889***********************6....69****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	5.3E-24	233	307	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.27E-19	235	304	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	17.346	236	286	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.82E-16	238	291	No hit	No description
Pfam	PF00010	7.9E-16	238	287	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.8E-13	242	292	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 310 aa Download sequence Send to blast
SKSWPEKQNI QGGYLKTHDF LQPLERVGKA TCAKEETSVE ISTSEKPPPP APPPVEHVLP 60 GGIGTYSISH ISYFNQIQSR VPKPEGMVYP AAQASSTDKN DENSNCSSFT GSGFTLWEEP 120 AVKKGKTGKE NMVVDKPGVV EPVARVGQWA STERPSQSSS SNHRGSFSSL SSSQPSAQRN 180 QSFMEMIKSA KGCSQDDEIE EEDQYILKKE ISTGTAQRGE LRVKVDGKSS DQKANTPRSK 240 HSATEQRRRS KINDRFQRLR ELIPNIDQKR DKASFLLEVI EYIQYLQEKV HKHEGSFQGW 300 ANEPAKLMPW

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269\|PubMed:15680330}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by cold treatment. {ECO:0000269\|PubMed:12679534}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024024837.1	1e-154	transcription factor BIM1 isoform X2
Swissprot	Q9LEZ3	8e-95	BIM1_ARATH; Transcription factor BIM1
TrEMBL	A0A2P5EBR7	1e-155	A0A2P5EBR7_TREOI; Basic helix-loop-helix transcription factor
STRING	XP_002514597.1	1e-138	(Ricinus communis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7252	31	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08130.5	6e-93	bHLH family protein

Publications ? help Back to Top
Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]