PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

HD-ZIP

Protein Properties

Length: 306aa MW: 34482.8 Da PI: 8.0917

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PGSC0003DMP400041776	genome	PGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.7	4.7e-19	135	189	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ ++tkeq +Le+ F+ +++++ +++ LAk+lgL rqV vWFqNrRa+ k PGSC0003DMP400041776 135 RKKLRLTKEQSAVLEDSFKDHHTLNPKQKLALAKRLGLRPRQVEVWFQNRRARTK 189 678899***********************************************98 PP
2	HD-ZIP_I/II	126.7	9.9e-41	135	224	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLre 89 +kk+rl+keq+++LE+sF+ +++L+p++K +la++Lgl+prqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l++en+rL+kev+eLr PGSC0003DMP400041776 135 RKKLRLTKEQSAVLEDSFKDHHTLNPKQKLALAKRLGLRPRQVEVWFQNRRARTKLKQTEVDCEFLKRCVENLTDENRRLQKEVQELR- 222 69*************************************************************************************9. PP HD-ZIP_I/II 90 el 91 +l PGSC0003DMP400041776 223 SL 224 55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	4.1E-31	1	108	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	1.04E-18	126	192	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.022	131	191	IPR001356	Homeobox domain
SMART	SM00389	1.1E-17	133	195	IPR001356	Homeobox domain
Pfam	PF00046	2.0E-16	135	189	IPR001356	Homeobox domain
CDD	cd00086	2.80E-16	135	192	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.1E-18	135	187	IPR009057	Homeodomain-like
PRINTS	PR00031	3.1E-5	162	171	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	166	189	IPR017970	Homeobox, conserved site
PRINTS	PR00031	3.1E-5	171	187	IPR000047	Helix-turn-helix motif
CDD	cd14686	0.00435	184	223	No hit	No description
Gene3D	G3DSA:1.20.5.170	8.5E-4	188	224	No hit	No description
SMART	SM00340	2.3E-25	191	234	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	4.5E-10	191	225	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 306 aa Download sequence Send to blast
MMGKEDLGLS LSLSFSAEKR TTTINLIPST IISPSSAFNN NYWTTHPPFP HSSPDLNTEA 60 CRLVETKSFL KGIDVNRMPA TAEEEEGGVS SPNSTISSLS GNKRSEREGN CTEENEMERA 120 SSRGISDEED GETCRKKLRL TKEQSAVLED SFKDHHTLNP KQKLALAKRL GLRPRQVEVW 180 FQNRRARTKL KQTEVDCEFL KRCVENLTDE NRRLQKEVQE LRSLKHSPQF YMQMTPPTTL 240 TMCPSCEHVA TGPTNTPVNI PPHRVGPPHQ HHQPMPLNMW GPSSTPISQG HYGQMDTYPT 300 FARQK*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	183	191	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PGSC0003DMP400041776

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975518	1e-162	HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006367464.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT4
Swissprot	P46600	2e-94	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	M1C8G7	0.0	M1C8G7_SOLTU; Uncharacterized protein
STRING	PGSC0003DMT400062081	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17460.1	1e-96	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein

Link Out ? help Back to Top
Phytozome	PGSC0003DMP400041776

Publications ? help Back to Top
Xu X, et al. Genome sequence and analysis of the tuber crop potato. Nature, 2011. 475(7355): p. 189-95 [PMID:21743474] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]