PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

bHLH

Protein Properties

Length: 149aa MW: 16910.9 Da PI: 10.4872

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PGSC0003DMP400033040	genome	PGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.2	6.9e-09	87	127	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR++i +++ L++l+P +K++ a++L +Av+Y+k L PGSC0003DMP400033040 87 ARHRREKISQKIRILQRLVPGG-----TKMDTASMLDEAVHYVKFL 127 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.951	78	127	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.8E-14	79	138	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.18E-7	80	126	No hit	No description
SuperFamily	SSF47459	4.06E-14	82	138	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.1E-12	84	133	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.8E-6	88	127	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 149 aa Download sequence Send to blast
MDLNEITQSI NNIEMIQLLP IHNSSSIDHE PALLPVPSIH ERSSLEMMRE MIFHIAMMQP 60 NKIDPESVKP PKRKNVKISK DPQSVAARHR REKISQKIRI LQRLVPGGTK MDTASMLDEA 120 VHYVKFLKKQ LKLLKQAIAC SNDNNKKG*

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PGSC0003DMP400033040

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC233061	1e-113	AC233061.1 Solanum lycopersicum chromosome 9 clone C09HBa0037P10, complete sequence.
GenBank	HG975515	1e-113	HG975515.1 Solanum lycopersicum chromosome ch03, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015170922.1	1e-104	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	3e-40	HEC2_ARATH; Transcription factor HEC2
TrEMBL	M1BMY6	1e-103	M1BMY6_SOLTU; Uncharacterized protein
STRING	PGSC0003DMT400048857	1e-104	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	9e-39	bHLH family protein

Link Out ? help Back to Top
Phytozome	PGSC0003DMP400033040
Entrez Gene	107063503

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Xu X, et al. Genome sequence and analysis of the tuber crop potato. Nature, 2011. 475(7355): p. 189-95 [PMID:21743474] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]