PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

bHLH

Protein Properties

Length: 254aa MW: 28318.1 Da PI: 9.0431

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PGSC0003DMP400014008	genome	PGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.4	1.2e-08	149	191	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ r RR+ri +++ L++l+P +K++ a++L +A++Y+k L PGSC0003DMP400014008 149 IAARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 191 56799***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.262	142	191	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.2E-13	147	200	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.75E-14	147	200	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.4E-14	148	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.7E-6	150	191	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.44E-6	165	196	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 254 aa Download sequence Send to blast
MDIDMLKSSA ASEDQMEMML MMQLEKFPDF YTGNCSELPM MEFSPQGSCN SSNNNNNNYN 60 FQQIDQNSPN FLNMPSTISF TNSPPIHQNP NFLPNSGGFT SNSMNRSNMA AMREMIFRIA 120 AMQPINIDPE SVKPPKRRNV KISTDPQSIA ARHRRERISE RIRILQRLVP GGTKMDTASM 180 LDEAIHYVKF LKNQVQSLER AGATRPANGT AVTAAAAAGL GFPVPMSLSG NYYNLPVSSK 240 NYHHQNIQRY ADV*

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PGSC0003DMP400014008

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975516	0.0	HG975516.1 Solanum lycopersicum chromosome ch04, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006354949.1	0.0	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	3e-48	HEC2_ARATH; Transcription factor HEC2
TrEMBL	M1ADQ0	0.0	M1ADQ0_SOLTU; Uncharacterized protein
STRING	PGSC0003DMT400020558	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	1e-42	bHLH family protein

Link Out ? help Back to Top
Phytozome	PGSC0003DMP400014008
Entrez Gene	102592363

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Xu X, et al. Genome sequence and analysis of the tuber crop potato. Nature, 2011. 475(7355): p. 189-95 [PMID:21743474] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]