PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

HD-ZIP

Protein Properties

Length: 773aa MW: 85945.9 Da PI: 6.5162

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PGSC0003DMP400004701	genome	PGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	65.9	5.4e-21	113	168	1	56
TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 r+k +++t +q++e+e+lF+++++p++++r++L+k+lgL rqVk+WFqNrR++ k PGSC0003DMP400004701 113 RKKYHRHTVQQIREMEALFKESPHPDEKQRQQLSKQLGLHPRQVKFWFQNRRTQIK 168 7999************************************************9877 PP
2	START	214.1	4.8e-67	287	509	3	206
HHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.....SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EE CS START 3 aeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv....dsgealrasgvvdmvlallveellddkeqWdetla....ka 79 ++a+++l k+a+++ep+W ks e++n+de++++f++++v +ea+r++g+v+m+l++lv++++d++ qW e+++ ka PGSC0003DMP400004701 287 VNQAMEQLTKMATSGEPLWIKSFetgrEILNYDEYTKEFPPGDVkskrMCIEASRDTGIVFMELPRLVQTFMDVN-QWREMFPsiisKA 374 5789****************99****************999999*********************.********* PP EEEEEECTT........EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECT CS START 80 etlevissg........galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksn 159 +t++vi++g ga+qlm+ae q+l+p+v R+++fvRy++q++a +w ivdvSvd + ++s+ ++++lpSg+++++ sn PGSC0003DMP400004701 375 ATVDVICNGteganswdGAVQLMFAEVQMLTPVVGtREVYFVRYCKQMSAAQWGIVDVSVDKVEGSI-DASLLKCRKLPSGCILQEQSN 462 *************************************************************87.9**************** PP CEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS START 160 ghskvtwvehvdlkgrlphwllrslvksglaegaktwvatlqrqcek 206 h+kvtwveh +++++++++l+r++v+sg+a+ga++w+atlq+qce+ PGSC0003DMP400004701 463 AHCKVTWVEHLECQKSIVDSLYRVTVNSGQAFGARRWMATLQQQCER 509 *******************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	4.6E-22	97	164	IPR009057	Homeodomain-like
SuperFamily	SSF46689	9.61E-21	98	171	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.799	110	170	IPR001356	Homeobox domain
SMART	SM00389	1.9E-18	112	174	IPR001356	Homeobox domain
Pfam	PF00046	2.8E-18	113	168	IPR001356	Homeobox domain
CDD	cd00086	2.17E-16	117	168	No hit	No description
PROSITE pattern	PS00027	0	145	168	IPR017970	Homeobox, conserved site
PROSITE profile	PS50848	35.066	276	512	IPR002913	START domain
SuperFamily	SSF55961	1.51E-30	278	509	No hit	No description
CDD	cd08875	6.93E-104	280	508	No hit	No description
SMART	SM00234	2.5E-62	285	509	IPR002913	START domain
Pfam	PF01852	3.7E-54	287	509	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	3.6E-4	288	505	IPR023393	START-like domain
SuperFamily	SSF55961	2.06E-12	552	760	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009957	Biological Process	epidermal cell fate specification
GO:0010062	Biological Process	negative regulation of trichoblast fate specification
GO:0005634	Cellular Component	nucleus
GO:0008289	Molecular Function	lipid binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 773 aa Download sequence Send to blast
MVVVDMSNNH PPSHETKDFF PSPALSLSLA GIFRDGGGAG SSAGNMETTE EVDEGSAAAS 60 RGGRPREETS TVEISSENSE QMRSRGSDDD LEHDDTCNED EEDPNNNSKK KKRKKYHRHT 120 VQQIREMEAL FKESPHPDEK QRQQLSKQLG LHPRQVKFWF QNRRTQIKAI QERHENSLLK 180 AEIEKLREEN KGLRGTSKNP SCPNCGFASS SNNAPTLPAE EQQLRIENAR LRAEVEKLRA 240 ALGKYPLGTS PNSSSSCSGG NDEENKSALD FYTGIFGLEK PRIMHIVNQA MEQLTKMATS 300 GEPLWIKSFE TGREILNYDE YTKEFPPGDV KSKRMCIEAS RDTGIVFMEL PRLVQTFMDV 360 NQWREMFPSI ISKAATVDVI CNGTEGANSW DGAVQLMFAE VQMLTPVVGT REVYFVRYCK 420 QMSAAQWGIV DVSVDKVEGS IDASLLKCRK LPSGCILQEQ SNAHCKVTWV EHLECQKSIV 480 DSLYRVTVNS GQAFGARRWM ATLQQQCERL LFFMATNIPT KDTTGVATLA GRKSILTLAQ 540 RMTWGFYRVL GASSYNTWNK VPSKTGQEDI RMTSRRNLTD PGEPQGLILC AVSSIWLPVS 600 RNVLFDFLKD ENHRHEWDVM SNGGPVQSVA NLAKGQDKGN AVSIQAVKLR ENNMWILQDT 660 CTNAYESAVV YAPVDIAGMQ SVITGCDSSN IAVLPSGFSI LPDGLESRPF VITSRPEDRS 720 SEGGSLLTVA FQILTSNSPT TKLSKESVES INNLLSCTLH KIKTRFQCDN GY*

Sequence ? help Back to Top

Protein Sequence Length: 773 aa Download sequence Send to blast

MVVVDMSNNH PPSHETKDFF PSPALSLSLA GIFRDGGGAG SSAGNMETTE EVDEGSAAAS  60
RGGRPREETS TVEISSENSE QMRSRGSDDD LEHDDTCNED EEDPNNNSKK KKRKKYHRHT  120
VQQIREMEAL FKESPHPDEK QRQQLSKQLG LHPRQVKFWF QNRRTQIKAI QERHENSLLK  180
AEIEKLREEN KGLRGTSKNP SCPNCGFASS SNNAPTLPAE EQQLRIENAR LRAEVEKLRA  240
ALGKYPLGTS PNSSSSCSGG NDEENKSALD FYTGIFGLEK PRIMHIVNQA MEQLTKMATS  300
GEPLWIKSFE TGREILNYDE YTKEFPPGDV KSKRMCIEAS RDTGIVFMEL PRLVQTFMDV  360
NQWREMFPSI ISKAATVDVI CNGTEGANSW DGAVQLMFAE VQMLTPVVGT REVYFVRYCK  420
QMSAAQWGIV DVSVDKVEGS IDASLLKCRK LPSGCILQEQ SNAHCKVTWV EHLECQKSIV  480
DSLYRVTVNS GQAFGARRWM ATLQQQCERL LFFMATNIPT KDTTGVATLA GRKSILTLAQ  540
RMTWGFYRVL GASSYNTWNK VPSKTGQEDI RMTSRRNLTD PGEPQGLILC AVSSIWLPVS  600
RNVLFDFLKD ENHRHEWDVM SNGGPVQSVA NLAKGQDKGN AVSIQAVKLR ENNMWILQDT  660
CTNAYESAVV YAPVDIAGMQ SVITGCDSSN IAVLPSGFSI LPDGLESRPF VITSRPEDRS  720
SEGGSLLTVA FQILTSNSPT TKLSKESVES INNLLSCTLH KIKTRFQCDN GY*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	108	113	KKKKRK
2	108	114	KKKKRKK
3	110	114	KKRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. {ECO:0000269\|PubMed:11844112}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	PGSC0003DMP400004701

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by GEM. {ECO:0000269\|PubMed:17450124}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975515	1e-176	HG975515.1 Solanum lycopersicum chromosome ch03, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006343080.1	0.0	PREDICTED: homeobox-leucine zipper protein GLABRA 2
Swissprot	P46607	0.0	HGL2_ARATH; Homeobox-leucine zipper protein GLABRA 2
TrEMBL	M0ZRY5	0.0	M0ZRY5_SOLTU; Uncharacterized protein
STRING	PGSC0003DMT400006770	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA6228	23	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79840.1	0.0	HD-ZIP family protein

Link Out ? help Back to Top
Phytozome	PGSC0003DMP400004701
Entrez Gene	102591633

Publications ? help Back to Top
Xu X, et al. Genome sequence and analysis of the tuber crop potato. Nature, 2011. 475(7355): p. 189-95 [PMID:21743474] Wu R,Citovsky V Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development. Biochem. Biophys. Res. Commun., 2017. 488(3): p. 547-553 [PMID:28526410]