PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

MYB_related

Protein Properties

Length: 325aa MW: 35497.6 Da PI: 10.1718

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_27771	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	35.3	2.7e-11	5	55	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT.....TTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg.....kgRtlkqcksrwqk 46 +++WT eE+ l+ +v ++G g W+tI + R+ ++k++w++ PEQU_27771 5 KQKWTSEEESALKAGVVKHGAGKWRTILKDPEfssvlSLRSNVDLKDKWRN 55 79*********************************88*********9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	12.546	1	61	IPR017930	Myb domain
SuperFamily	SSF46689	4.45E-15	2	68	IPR009057	Homeodomain-like
SMART	SM00717	4.3E-6	4	59	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-7	5	55	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.7E-13	5	56	IPR009057	Homeodomain-like
CDD	cd11660	1.84E-18	6	56	No hit	No description
SMART	SM00526	7.6E-15	117	183	IPR005818	Linker histone H1/H5, domain H15
PROSITE profile	PS51504	22.328	120	188	IPR005818	Linker histone H1/H5, domain H15
SuperFamily	SSF46785	8.71E-16	123	199	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	5.3E-15	124	192	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00538	1.7E-9	124	181	IPR005818	Linker histone H1/H5, domain H15

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006334	Biological Process	nucleosome assembly
GO:0006357	Biological Process	regulation of transcription from RNA polymerase II promoter
GO:0009651	Biological Process	response to salt stress
GO:0009723	Biological Process	response to ethylene
GO:0009733	Biological Process	response to auxin
GO:0009737	Biological Process	response to abscisic acid
GO:0009739	Biological Process	response to gibberellin
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0046686	Biological Process	response to cadmium ion
GO:0000786	Cellular Component	nucleosome
GO:0005730	Cellular Component	nucleolus
GO:0003691	Molecular Function	double-stranded telomeric DNA binding
GO:0033613	Molecular Function	activating transcription factor binding
GO:0042803	Molecular Function	protein homodimerization activity
GO:0070491	Molecular Function	repressing transcription factor binding
GO:1990841	Molecular Function	promoter-specific chromatin binding

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MGAPKQKWTS EEESALKAGV VKHGAGKWRT ILKDPEFSSV LSLRSNVDLK DKWRNMSVTA 60 HGWGSREKAR MALKKSQPIS KQEEGPLALS IVDDHDDEIV DGKPLAQASP LPLLTAPRKL 120 VSKIDSLIFE AITNLKEPGG SNKTAITMYI EDQYSAPPNL KKLLSGKLKA LTANGKLSKV 180 KRRYRIAQTS AQSEHRRTKS KALLPEGRQK ESSRVDNKKD IKALSKPQID AELARMRNMT 240 AEEAAVAAAQ AVAEAEEAIA EAEEAARDAE AAEADAEAAE AFAEAALKAL KKRAKSVMSP 300 SLYAQHFSLK VYKNVKLVLG FFNEG

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	289	295	LKKRAKS

Functional Description ? help Back to Top
Source	Description
UniProt	Binds preferentially double-stranded telomeric repeats. {ECO:0000269\|PubMed:19102728}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00607	ChIP-seq	Transfer from AT1G49950	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020592412.1	0.0	telomere repeat-binding factor 1
Swissprot	Q8VWK4	3e-89	TRB1_ARATH; Telomere repeat-binding factor 1
TrEMBL	A0A2I0VZT4	1e-142	A0A2I0VZT4_9ASPA; Telomere repeat-binding factor 1
STRING	XP_010263289.1	1e-108	(Nelumbo nucifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1324	38	110

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G49950.3	6e-83	telomere repeat binding factor 1

Publications ? help Back to Top
Alexandrov NN, et al. Features of Arabidopsis genes and genome discovered using full-length cDNAs. Plant Mol. Biol., 2006. 60(1): p. 69-85 [PMID:16463100] Schrumpfová PP, et al. Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase. Plant J., 2014. 77(5): p. 770-81 [PMID:24397874] Liang SC, et al. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet., 2015. 11(12): p. e1005660 [PMID:26642436] Fulcher N,Riha K Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana. Front Genet, 2015. 6: p. 349 [PMID:26779251] Kotliński M, et al. Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain. Plant Physiol., 2017. 174(1): p. 27-34 [PMID:28298478]