PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PEQU_16534

Organism

Phalaenopsis equestris

Taxonomic ID

78828

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

E2F/DP

Protein Properties

Length: 436aa MW: 47915.8 Da PI: 5.0181

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_16534	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	82.5	3.5e-26	154	219	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++e+g+++ln++a+ L dv ++RRiYDi+NVLe+++li k+ kn+i+wkg PEQU_16534 154 RYDSSLGLLTKKFINLLQQAEDGTLDLNKAAEIL---DV--QKRRIYDITNVLEGVGLIVKQLKNQIHWKG 219 6899****************************.....****************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.6E-27	151	221	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	9.7E-34	154	219	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.56E-16	154	217	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.1E-23	156	219	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	6.69E-40	230	338	No hit	No description
SuperFamily	SSF144074	9.68E-27	231	337	No hit	No description
Pfam	PF16421	3.2E-27	235	335	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 436 aa Download sequence Send to blast
MAGAADSTFS IENPSIHQPQ SPPARPASSQ ILCPGSKQHL PFPPSSSTAS AAFDRRILTG 60 VTASVVDESR DGKEMFPALE PSLKIVDGKI DRAGASGQFV AEKEQKEVAR NHKSSSIIGV 120 KRQRNPKSSR NKKSVPSYTG PSDGNPVSAL STCRYDSSLG LLTKKFINLL QQAEDGTLDL 180 NKAAEILDVQ KRRIYDITNV LEGVGLIVKQ LKNQIHWKGF NMSRPMEVGA EIAGLKAELQ 240 SLESEDCRLD AMICNMQENL LSFSEDESNQ KWLYLTKEDI SCIPCFQQNS TLIAVKAPHG 300 TSLEVPNPDE GLEFPQRQYQ MLLRSSMGPV DCYLLSNHEE RFEASNLDQH FASMDLSVQN 360 SCTSMHHLMV PRPGDGHILS TADQEQIEAD RSTLDADILR DSEGGIVKIT PCDDVSDYWL 420 LSEGGGYGIS ESWRTS

Sequence ? help Back to Top

Protein Sequence Length: 436 aa Download sequence Send to blast

MAGAADSTFS IENPSIHQPQ SPPARPASSQ ILCPGSKQHL PFPPSSSTAS AAFDRRILTG  60
VTASVVDESR DGKEMFPALE PSLKIVDGKI DRAGASGQFV AEKEQKEVAR NHKSSSIIGV  120
KRQRNPKSSR NKKSVPSYTG PSDGNPVSAL STCRYDSSLG LLTKKFINLL QQAEDGTLDL  180
NKAAEILDVQ KRRIYDITNV LEGVGLIVKQ LKNQIHWKGF NMSRPMEVGA EIAGLKAELQ  240
SLESEDCRLD AMICNMQENL LSFSEDESNQ KWLYLTKEDI SCIPCFQQNS TLIAVKAPHG  300
TSLEVPNPDE GLEFPQRQYQ MLLRSSMGPV DCYLLSNHEE RFEASNLDQH FASMDLSVQN  360
SCTSMHHLMV PRPGDGHILS TADQEQIEAD RSTLDADILR DSEGGIVKIT PCDDVSDYWL  420
LSEGGGYGIS ESWRTS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-21	154	219	7	73	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020572214.1	0.0	transcription factor E2FB-like isoform X1
Refseq	XP_020572215.1	0.0	transcription factor E2FB-like isoform X2
Swissprot	Q9FV71	1e-86	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2I0WRL9	0.0	A0A2I0WRL9_9ASPA; Transcription factor E2FB
STRING	XP_008785127.1	1e-120	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	6e-89	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]