PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

C2H2

Protein Properties

Length: 406aa MW: 45262.3 Da PI: 7.9467

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_15342	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.2	2.9e-05	6	28	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C+ C+k F r nL+ H r H PEQU_15342 6 FICEVCSKGFQREQNLQLHRRGH 28 89*******************88 PP
2	zf-C2H2	13.1	0.00029	78	100	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H +t+ PEQU_15342 78 WKCDKCSKRYAVQSDWKAHSKTC 100 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.37E-9	5	28	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.5E-5	5	28	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	7.5E-5	6	28	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.928	6	28	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.011	6	28	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	8	28	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.37E-9	73	98	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.2E-4	73	99	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	140	78	98	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 406 aa Download sequence Send to blast
MATNRFICEV CSKGFQREQN LQLHRRGHNL PWKLKQKSNK EVRRRVYLCP EPSCVHHDPS 60 RALGDLTGIS RKHGEKKWKC DKCSKRYAVQ SDWKAHSKTC GTREYRCDCG TLFSRRDSFI 120 THRAFCDALA QESSRLPTIG SHFYRNNNNN NNFALSHHLS SLHYQNQNHQ ISPELLRPTT 180 FFLTGDDALQ TKPSFHGLIH LPDLQPNSHN TSSSPSNPFN LSFFSNNNQN SQFINSSGNL 240 MNDQMQAVFS NGVLPQMSAT ALLQKAAEMG ATSSLGEQNL RAQVENHEKH LMDIMNSFAN 300 GSPGVFVGGG GGEEEEVDVK FAEFDDAGLC NMEEGRYQNN GLTRDFLGVG SMLRSMGGGI 360 GLDHGGINKS VSSNRLYHAG SFGSGRREMG EEEEEEMRGN GGNGLR

Sequence ? help Back to Top

Protein Sequence Length: 406 aa Download sequence Send to blast

MATNRFICEV CSKGFQREQN LQLHRRGHNL PWKLKQKSNK EVRRRVYLCP EPSCVHHDPS  60
RALGDLTGIS RKHGEKKWKC DKCSKRYAVQ SDWKAHSKTC GTREYRCDCG TLFSRRDSFI  120
THRAFCDALA QESSRLPTIG SHFYRNNNNN NNFALSHHLS SLHYQNQNHQ ISPELLRPTT  180
FFLTGDDALQ TKPSFHGLIH LPDLQPNSHN TSSSPSNPFN LSFFSNNNQN SQFINSSGNL  240
MNDQMQAVFS NGVLPQMSAT ALLQKAAEMG ATSSLGEQNL RAQVENHEKH LMDIMNSFAN  300
GSPGVFVGGG GGEEEEVDVK FAEFDDAGLC NMEEGRYQNN GLTRDFLGVG SMLRSMGGGI  360
GLDHGGINKS VSSNRLYHAG SFGSGRREMG EEEEEEMRGN GGNGLR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-35	74	139	3	68	Zinc finger protein JACKDAW
5b3h_F	2e-35	74	139	3	68	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that may act a transcriptional activator of nuclear-encoded photosynthetic gene expression (Probable). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:24821766, ECO:0000305\|PubMed:19726569}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000305\|PubMed:17933900}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020575080.1	0.0	LOW QUALITY PROTEIN: protein indeterminate-domain 5, chloroplastic-like
Swissprot	Q8GYC1	2e-96	IDD4_ARATH; Protein indeterminate-domain 4, chloroplastic
TrEMBL	A0A2I0XAH0	0.0	A0A2I0XAH0_9ASPA; Zinc finger protein MAGPIE
STRING	XP_008804317.1	1e-131	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1733	37	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G14580.2	1e-93	C2H2-like zinc finger protein

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]