PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

Dof

Protein Properties

Length: 258aa MW: 28274.3 Da PI: 8.7858

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_13748	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	127	5.6e-40	45	105	2	62
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 +e++l+cprCdstntkfCyynnyslsqPryfCk+CrryWtkGG+lrnvPvGgg+rknk+ss PEQU_13748 45 PEQSLRCPRCDSTNTKFCYYNNYSLSQPRYFCKSCRRYWTKGGSLRNVPVGGGCRKNKRSS 105 78999*****************************************************975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	2.0E-28	36	99	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.1E-33	47	103	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.609	49	103	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	51	87	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0048364	Biological Process	root development
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 258 aa Download sequence Send to blast
MEISNGHHQV MATHQHDHEV LKLPKPSSSP THHLHQQEKK SRPQPEQSLR CPRCDSTNTK 60 FCYYNNYSLS QPRYFCKSCR RYWTKGGSLR NVPVGGGCRK NKRSSPSSST SSKKLGLQHH 120 QDINHSSLLI SSMPLPPPLN YDPSDLTLAF SSFHNHDTFL LGTPNSNPNP NPNASTGVGL 180 HSFYYGFSGG ADDVRGMLPF DSTAVAAETV MVGNFDPASN VNSTSTSHGS LGMESGRDYW 240 SGVGSNSSWH GLINSSLL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:30626969}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cytokinin in procambium (PubMed:30626969). Induced by the transcription factor MONOPTEROS (MP) in cells relevant for root initiation, and later in vascular tissues and hypophysis (PubMed:20220754). {ECO:0000269\|PubMed:20220754, ECO:0000269\|PubMed:30626969}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020571739.1	0.0	dof zinc finger protein DOF3.1-like
Swissprot	Q84TE9	6e-41	DOF53_ARATH; Dof zinc finger protein DOF5.3
TrEMBL	A0A2I0X8M4	1e-114	A0A2I0X8M4_9ASPA; Dof zinc finger protein DOF5.3
STRING	XP_008789033.1	6e-69	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP4704	32	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G60200.1	4e-38	TARGET OF MONOPTEROS 6

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]