PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

G2-like

Protein Properties

Length: 306aa MW: 33704.2 Da PI: 7.0106

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_09213	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95.4	4.5e-30	136	189	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl PEQU_09213 136 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVDGLTRENVASHLQKYRL 189 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.958	133	192	IPR017930	Myb domain
SuperFamily	SSF46689	2.15E-19	134	193	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.5E-30	135	194	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.1E-23	137	189	IPR006447	Myb domain, plants
Pfam	PF00249	5.2E-8	139	188	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 306 aa Download sequence Send to blast
MQGDDVEVLQ WVEGLPSGDD LIPLSQPLVS PLLASAFCIT PPELKTMLDI HRATQHTASN 60 LRRQQHLAKS SQIVSPLKPL SAADPKEPSD SQKPTLCPDD GAGASEVATM AEIEADSSSL 120 HAENSADDNS GRMLKRPRLV WTPQLHKRFV DVVAHLGIKN AVPKTIMQLM NVDGLTRENV 180 ASHLQKYRLY VKRMQGLSDE GPSTSDHLFA STPVPPQSFQ EQPMQHPMPY VVPAMIPMQV 240 YSIPHHHAHG LVPVNNRQGG QLFNGFDSFQ SYAPVDWSGR SKFASVVSKT YVSPNDNIRT 300 GEKQKQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	2e-33	136	192	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020577736.1	0.0	transcription factor PCL1-like
Swissprot	Q9SNB4	1e-71	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A2I0XFW9	1e-168	A0A2I0XFW9_9ASPA; Two-component response regulator ARR1
STRING	XP_008801647.1	6e-99	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1620	34	105

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.3	3e-74	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]