PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; Asparagales; Orchidaceae; Epidendroideae; Vandeae; Aeridinae; Phalaenopsis

Family

NAC

Protein Properties

Length: 324aa MW: 37112.7 Da PI: 7.5795

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PEQU_08525	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	169.1	1.4e-52	11	140	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96 +ppGfrFhPt+eel+ +yL+kkv+ + ++l +vi++vd++k+ePwdL+ k k+ + ++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++ ++ PEQU_08525 11 VPPGFRFHPTEEELLYYYLRKKVAYEAIDL-DVIRDVDLNKLEPWDLNdKcKIGSgPQNEWYFFSHKDKKYPTGTRTNRATTAGFWKATGRDKAIHISS 108 69**************************.9***********843444443456************************************ PP NAM 97 gelvglkktLvfykgrapkgektdWvmheyrl 128 ++ +g++ktLvfy+grap+g ktdW+mheyrl PEQU_08525 109 SKRIGMRKTLVFYTGRAPHGLKTDWIMHEYRL 140 ****************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	5.89E-59	7	160	IPR003441	NAC domain
PROSITE profile	PS51005	57.712	11	160	IPR003441	NAC domain
Pfam	PF02365	3.0E-27	12	140	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003002	Biological Process	regionalization
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009834	Biological Process	plant-type secondary cell wall biogenesis
GO:0010455	Biological Process	positive regulation of cell fate commitment
GO:0048829	Biological Process	root cap development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 324 aa Download sequence Send to blast
MNSNGNGQLA VPPGFRFHPT EEELLYYYLR KKVAYEAIDL DVIRDVDLNK LEPWDLNDKC 60 KIGSGPQNEW YFFSHKDKKY PTGTRTNRAT TAGFWKATGR DKAIHISSSK RIGMRKTLVF 120 YTGRAPHGLK TDWIMHEYRL DDDTSEIQED SWVVCRVFKK KSLYKCNNIP SDQILPQETN 180 LNLFKTTPCP NLFPQTQPHP SFDHFSFLNN NNNNNNNNNT MHLPQLLNSD QPSAAAVAAS 240 ASFITPIDLE CSQNLMKLTG DWSILDKLLA SNHQSQLDQF FHVKYNSTSS SSQQLMEMSS 300 SAQRFFPLQY FGCEADLLKF SKEG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	5e-51	8	162	14	167	NO APICAL MERISTEM PROTEIN
1ut4_B	5e-51	8	162	14	167	NO APICAL MERISTEM PROTEIN
1ut7_A	5e-51	8	162	14	167	NO APICAL MERISTEM PROTEIN
1ut7_B	5e-51	8	162	14	167	NO APICAL MERISTEM PROTEIN
3swm_A	5e-51	8	162	17	170	NAC domain-containing protein 19
3swm_B	5e-51	8	162	17	170	NAC domain-containing protein 19
3swm_C	5e-51	8	162	17	170	NAC domain-containing protein 19
3swm_D	5e-51	8	162	17	170	NAC domain-containing protein 19
3swp_A	5e-51	8	162	17	170	NAC domain-containing protein 19
3swp_B	5e-51	8	162	17	170	NAC domain-containing protein 19
3swp_C	5e-51	8	162	17	170	NAC domain-containing protein 19
3swp_D	5e-51	8	162	17	170	NAC domain-containing protein 19
4dul_A	5e-51	8	162	14	167	NAC domain-containing protein 19
4dul_B	5e-51	8	162	14	167	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00250	DAP	Transfer from AT1G79580	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269\|PubMed:19081078}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020587811.1	0.0	protein SOMBRERO
Swissprot	Q9MA17	1e-101	SMB_ARATH; Protein SOMBRERO
TrEMBL	A0A2I0XBM9	0.0	A0A2I0XBM9_9ASPA; Protein SOMBRERO
STRING	XP_008783883.1	1e-137	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP3461	37	81

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79580.3	5e-92	NAC family protein

Publications ? help Back to Top
Fendrych M, et al. Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis. Curr. Biol., 2014. 24(9): p. 931-40 [PMID:24726156] Bennett T,van den Toorn A,Willemsen V,Scheres B Precise control of plant stem cell activity through parallel regulatory inputs. Development, 2014. 141(21): p. 4055-64 [PMID:25256342] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Kamiya M, et al. Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis. Development, 2016. 143(21): p. 4063-4072 [PMID:27803060]