PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Coryphoideae; Phoeniceae; Phoenix

Family

G2-like

Protein Properties

Length: 466aa MW: 50961 Da PI: 5.8904

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PDK_30s681141g002	genome	PDK	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	108.8	2.8e-34	201	255	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr+rWtpeLHe+Fv+av+qLGGsekAtPk +l+lmkv++Lt++hvkSHLQkYR+ PDK_30s681141g002 201 KPRMRWTPELHECFVDAVNQLGGSEKATPKGVLKLMKVESLTIYHVKSHLQKYRT 255 79****************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.748	198	258	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	1.9E-32	199	257	IPR009057	Homeodomain-like
SuperFamily	SSF46689	6.63E-18	200	255	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	2.2E-25	201	255	IPR006447	Myb domain, plants
Pfam	PF00249	2.3E-9	203	254	IPR001005	SANT/Myb domain
Pfam	PF14379	1.7E-24	322	366	IPR025756	MYB-CC type transcription factor, LHEQLE-containing domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 466 aa Download sequence Send to blast
MERELRSTPL IPLRTPFVSN SAVVGPLYSS ASGFSSDLHF SSMAPNERHH NGASFVSQSP 60 NVGIPFPSTP SHSGSFCPAT SNHPRESADV SWCPEPIQGM LDYSDNITAG NNQIQSSCDV 120 ASDDLAKQNE WWTDLMNDDW KDILNETSAS ECQTKSVQPA TQASPSISVH QLQIHQSVPS 180 HSGELCAVSN SSPAAIAAAA KPRMRWTPEL HECFVDAVNQ LGGSEKATPK GVLKLMKVES 240 LTIYHVKSHL QKYRTARYRP DSSEGASQKK VTPQEEVSSL DLKTVSNILM KTPKIREDPE 300 IGKSVTGCLN ISMMQISFRS IDLTEALRLQ MEVQKRLHEQ LEIQRNLQLR IEEQGRYLQM 360 MFEKQSGISN LQASSSLEEP LTVSSDQTHS AAKIELPGKG RDESGIDPNG AKMSEGSRQV 420 GDKQKTLEAE SCNEMEANIV SGSHSPSCKR ARGPDGESLT PMSALD

Sequence ? help Back to Top

Protein Sequence Length: 466 aa Download sequence Send to blast

MERELRSTPL IPLRTPFVSN SAVVGPLYSS ASGFSSDLHF SSMAPNERHH NGASFVSQSP  60
NVGIPFPSTP SHSGSFCPAT SNHPRESADV SWCPEPIQGM LDYSDNITAG NNQIQSSCDV  120
ASDDLAKQNE WWTDLMNDDW KDILNETSAS ECQTKSVQPA TQASPSISVH QLQIHQSVPS  180
HSGELCAVSN SSPAAIAAAA KPRMRWTPEL HECFVDAVNQ LGGSEKATPK GVLKLMKVES  240
LTIYHVKSHL QKYRTARYRP DSSEGASQKK VTPQEEVSSL DLKTVSNILM KTPKIREDPE  300
IGKSVTGCLN ISMMQISFRS IDLTEALRLQ MEVQKRLHEQ LEIQRNLQLR IEEQGRYLQM  360
MFEKQSGISN LQASSSLEEP LTVSSDQTHS AAKIELPGKG RDESGIDPNG AKMSEGSRQV  420
GDKQKTLEAE SCNEMEANIV SGSHSPSCKR ARGPDGESLT PMSALD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6j4k_A	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j4k_B	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_A	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_C	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_D	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_F	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_H	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_J	2e-30	200	259	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in phosphate starvation signaling. Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes. Functionally redundant with PHR1 and PHR3 in regulating Pi starvation response and Pi homeostasis. PHR2 binding to DNA is repressed redundantly by SPX1, SPX2 and SPX4 in a PI-dependent manner. {ECO:0000250\|UniProtKB:Q6Z156}.
UniProt	Transcription factor involved in phosphate starvation signaling (PubMed:18263782, PubMed:26082401). Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes (PubMed:25657119, PubMed:26082401). Functionally redundant with PHR1 and PHR3 in regulating Pi starvation response and Pi homeostasis (PubMed:26082401). Involved in both systematic and local Pi-signaling pathways (PubMed:19704822). Regulates several Pi transporters (PubMed:18263782). Regulates the expression of PT2 (PubMed:20149131). Directly up-regulates SPX1 and SPX2 expression, but PHR2 binding to DNA is repressed redundantly by SPX1 and SPX2 in a PI-dependent manner (PubMed:25271318). The DNA-binding activity is also repressed by SPX4 (PubMed:24692424). Involved in root growth under Pi deprivation (PubMed:18263782). {ECO:0000269\|PubMed:18263782, ECO:0000269\|PubMed:19704822, ECO:0000269\|PubMed:20149131, ECO:0000269\|PubMed:24692424, ECO:0000269\|PubMed:25271318, ECO:0000269\|PubMed:25657119, ECO:0000269\|PubMed:26082401}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by Pi starvation. {ECO:0000269\|PubMed:18263782, ECO:0000269\|PubMed:26082401}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008785163.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2-like
Refseq	XP_008785164.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2-like
Swissprot	B8B5N8	1e-107	PHR2_ORYSI; Protein PHOSPHATE STARVATION RESPONSE 2
Swissprot	Q6Z156	1e-107	PHR2_ORYSJ; Protein PHOSPHATE STARVATION RESPONSE 2
TrEMBL	A0A2H3XKJ4	0.0	A0A2H3XKJ4_PHODC; protein PHOSPHATE STARVATION RESPONSE 2-like
STRING	XP_008785163.1	0.0	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1971	37	89

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G28610.1	1e-77	phosphate starvation response 1

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Wang C, et al. Involvement of OsSPX1 in phosphate homeostasis in rice. Plant J., 2009. 57(5): p. 895-904 [PMID:19000161] Zhang Q,Wang C,Tian J,Li K,Shou H Identification of rice purple acid phosphatases related to phosphate starvation signalling. Plant Biol (Stuttg), 2011. 13(1): p. 7-15 [PMID:21143719] Wu Z,Ren H,McGrath SP,Wu P,Zhao FJ Investigating the contribution of the phosphate transport pathway to arsenic accumulation in rice. Plant Physiol., 2011. 157(1): p. 498-508 [PMID:21715673] Chen J, et al. OsPHF1 regulates the plasma membrane localization of low- and high-affinity inorganic phosphate transporters and determines inorganic phosphate uptake and translocation in rice. Plant Physiol., 2011. 157(1): p. 269-78 [PMID:21753117] Wang C, et al. Functional characterization of the rice SPX-MFS family reveals a key role of OsSPX-MFS1 in controlling phosphate homeostasis in leaves. New Phytol., 2012. 196(1): p. 139-48 [PMID:22803610] Tian J, et al. Overexpression of OsPAP10a, a root-associated acid phosphatase, increased extracellular organic phosphorus utilization in rice. J Integr Plant Biol, 2012. 54(9): p. 631-9 [PMID:22805094] Shen C, et al. OsARF16, a transcription factor, is required for auxin and phosphate starvation response in rice (Oryza sativa L.). Plant Cell Environ., 2013. 36(3): p. 607-20 [PMID:22913536] Wu P,Shou H,Xu G,Lian X Improvement of phosphorus efficiency in rice on the basis of understanding phosphate signaling and homeostasis. Curr. Opin. Plant Biol., 2013. 16(2): p. 205-12 [PMID:23566853] Wang S, et al. Auxin response factor (OsARF12), a novel regulator for phosphate homeostasis in rice (Oryza sativa). New Phytol., 2014. 201(1): p. 91-103 [PMID:24111723] Shi J, et al. The paralogous SPX3 and SPX5 genes redundantly modulate Pi homeostasis in rice. J. Exp. Bot., 2014. 65(3): p. 859-70 [PMID:24368504] Li S,Wang C,Zhou L,Shou H Oxygen deficit alleviates phosphate overaccumulation toxicity in OsPHR2 overexpression plants. J. Plant Res., 2014. 127(3): p. 433-40 [PMID:24687599] Zhou Z, et al. SPX proteins regulate Pi homeostasis and signaling in different subcellular level. Plant Signal Behav, 2015. 10(9): p. e1061163 [PMID:26224365] Zhang K, et al. Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice. Plant Biotechnol. J., 2016. 14(8): p. 1661-72 [PMID:26806409] Cao Y, et al. Identification and expression analysis of OsLPR family revealed the potential roles of OsLPR3 and 5 in maintaining phosphate homeostasis in rice. BMC Plant Biol., 2016. 16(1): p. 210 [PMID:27716044]