PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100228250231
Organism
Ocimum tenuiflorum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family HD-ZIP
Protein Properties Length: 695aa    MW: 77080.6 Da    PI: 6.8114
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100228250231genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox61.31.5e-191873156
                                  TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                      Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                                  +++ +++t++q+++Le+lF+++ +p++++r +L+++l+L  rq+k+WFqNrR+++k
  Ote100228250231|100228250231 18 KKRYHRHTAHQIQRLESLFKECAHPDEKTRNQLSRELNLHPRQIKFWFQNRRTQMK 73
                                  688999***********************************************998 PP
2START153.41.8e-4825642944206
                                   CEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEE CS
                         START  44 sgealrasgvvdmvlallveellddkeqWdetla....kaetlevissg......galqlmvaelqalsplvp.RdfvfvR 113
                                   ++ea+r+sgvv+m+   lve ++d + +W e ++    +a t+ev+ssg      g lqlm+aelq+ls lvp R+ +f+R
  Ote100228250231|100228250231 256 RTEASRDSGVVIMNDLALVEMFVDAN-KWMELFPgivaRARTIEVLSSGmmgshsGSLQLMYAELQVLSALVPtRKLYFLR 335
                                   689***********************.****************************************************** PP

                                   EEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHH CS
                         START 114 yirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaega 193
                                   + +q +ag+wv+vdvS d +++ ++ ss+ +a++lpSg+li++++ng+skvtwveh+++++++  h l+r l++sgla+ga
  Ote100228250231|100228250231 336 FVQQIEAGSWVVVDVSYDIPNQESQFSSSSKAHMLPSGCLIQEMPNGYSKVTWVEHWEVEDKSAvHRLYRDLIHSGLAFGA 416
                                   ******************99999999999******************************999988**************** PP

                                   HHHHHHTXXXXXX CS
                         START 194 ktwvatlqrqcek 206
                                    +w+  lqr ce+
  Ote100228250231|100228250231 417 ERWLPNLQRMCER 429
                                   ***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.96E-191178IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.5E-211480IPR009057Homeodomain-like
PROSITE profilePS5007116.8271575IPR001356Homeobox domain
SMARTSM003891.5E-181679IPR001356Homeobox domain
CDDcd000862.77E-181776No hitNo description
PfamPF000464.3E-171873IPR001356Homeobox domain
PROSITE patternPS0002705073IPR017970Homeobox, conserved site
SMARTSM002341.1E-31217429IPR002913START domain
CDDcd088751.78E-92253428No hitNo description
PfamPF018529.0E-41256429IPR002913START domain
SuperFamilySSF559615.86E-28256430No hitNo description
PROSITE profilePS5084835.532258432IPR002913START domain
Gene3DG3DSA:3.30.530.201.0E-6291413IPR023393START-like domain
SuperFamilySSF559615.13E-19450683No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 695 aa     Download sequence    Send to blast
MEFSTGGSSG GDAPDGRKKR YHRHTAHQIQ RLESLFKECA HPDEKTRNQL SRELNLHPRQ  60
IKFWFQNRRT QMKAQHERAD NCTLRADNDR IRCENIAMRE ALRNIICPSC GVTQDSYFDE  120
QKLRIENAHL KEELDRVSSI AAKYIGRPIS QLPPVQPIHV PSLDLSMASF GGHGLLPSPS  180
LDLDLLSFPP MSISDVDKSL MADVAAXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX  240
XXXXXXXXXX KNPGIRTEAS RDSGVVIMND LALVEMFVDA NKWMELFPGI VARARTIEVL  300
SSGMMGSHSG SLQLMYAELQ VLSALVPTRK LYFLRFVQQI EAGSWVVVDV SYDIPNQESQ  360
FSSSSKAHML PSGCLIQEMP NGYSKVTWVE HWEVEDKSAV HRLYRDLIHS GLAFGAERWL  420
PNLQRMCERI ACFMVAANSN REVGGAVPSP EGTRSMMKLA QRMVSNFCAS INPSSGQHLT  480
TLLGSSELEV RATLYRSIDP GHSNRMVLSA AATIWVPVSP HNVFDFLRDE RNRPQWDVLS  540
NQNPVQEVAH IANGSHPGNC ISVLRASNTS QNNMLILQES CLDSSGCLVV YCPVDLSSIN  600
VAMSGEDTSF IPLLPSGFTI TPDGVGSCDG ASTSSNLDPS ARSSASSLVT VVFQILVSNM  660
PTARISPETV NTVNNLIGNT VHHIKAAMNC SRHDL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011072039.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A4D8YQW40.0A0A4D8YQW4_SALSN; Homeobox-leucine zipper protein
STRINGMigut.O00242.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]