PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza

Family

bHLH

Protein Properties

Length: 553aa MW: 60322.6 Da PI: 5.0261

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
ORGLA04G0183800.1	genome	AGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40.6	4.6e-13	377	423	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++h + ErrRR+++N+ f L++++P+ K++Ka+iLe+++ Y+k L ORGLA04G0183800.1 377 KNHVISERRRREKLNEMFLILKSIVPSiH------KVDKASILEETIAYLKVL 423 57999********************66......*************977 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	4.9E-51	21	202	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	15.834	374	423	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.17E-15	377	428	No hit	No description
SuperFamily	SSF47459	1.57E-17	377	444	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.6E-10	378	423	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.7E-16	378	441	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.6E-14	380	429	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010026	Biological Process	trichome differentiation
GO:0010214	Biological Process	seed coat development
GO:2000029	Biological Process	regulation of proanthocyanidin biosynthetic process
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 553 aa Download sequence Send to blast
MASAPPVQEE PLQPGTNHFR SLLAAAVRSI SWSYAIFWSI STSCPGVLTW NDGFYNGVVK 60 TRKISKSADL TAGQLVVQRS EQLRELYYSL LSGECDHRAR RPIAALSPED LADTEWYYVV 120 CMTYSFQPGQ GLPGKSYASN ASVWLRNAQS ADSKTFLRSL LAKSASIQTI ICIPFTSGVL 180 ELGTTDPVLE DPNLVNRIVA YFQELQFPIC LEVLMSTSPS PNETEDADIV SEGLITHNAI 240 EEGQMVVSDE CVSNANRDPI TMEIDELYSI YEDLDLDTVR FLEDNGWPVN PSSFQLVPAS 300 STEAVAAAAA ANDVDGVANS QVSCFMAWKS AKSNEMAVPV VTGIESQKLL KKVVDCGARM 360 STGRGSRAAL TQESGIKNHV ISERRRREKL NEMFLILKSI VPSIHKVDKA SILEETIAYL 420 KVLEKRVKEL ESSSEPSHQR ATETGQQRRC EITGKELVSE IGVSGGGDAG REHHHVNVTV 480 TDKVVLLEVQ CRWKELVMTR VFDAIKSLCL DVLSVQASAP DGLLGLKIQA KFACSGSVAP 540 GMISEALQKA IGG

Sequence ? help Back to Top

Protein Sequence Length: 553 aa Download sequence Send to blast

MASAPPVQEE PLQPGTNHFR SLLAAAVRSI SWSYAIFWSI STSCPGVLTW NDGFYNGVVK  60
TRKISKSADL TAGQLVVQRS EQLRELYYSL LSGECDHRAR RPIAALSPED LADTEWYYVV  120
CMTYSFQPGQ GLPGKSYASN ASVWLRNAQS ADSKTFLRSL LAKSASIQTI ICIPFTSGVL  180
ELGTTDPVLE DPNLVNRIVA YFQELQFPIC LEVLMSTSPS PNETEDADIV SEGLITHNAI  240
EEGQMVVSDE CVSNANRDPI TMEIDELYSI YEDLDLDTVR FLEDNGWPVN PSSFQLVPAS  300
STEAVAAAAA ANDVDGVANS QVSCFMAWKS AKSNEMAVPV VTGIESQKLL KKVVDCGARM  360
STGRGSRAAL TQESGIKNHV ISERRRREKL NEMFLILKSI VPSIHKVDKA SILEETIAYL  420
KVLEKRVKEL ESSSEPSHQR ATETGQQRRC EITGKELVSE IGVSGGGDAG REHHHVNVTV  480
TDKVVLLEVQ CRWKELVMTR VFDAIKSLCL DVLSVQASAP DGLLGLKIQA KFACSGSVAP  540
GMISEALQKA IGG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	6e-19	5	202	2	192	Transcription factor MYC3
4rqw_B	6e-19	5	202	2	192	Transcription factor MYC3
4rs9_A	6e-19	5	202	2	192	Transcription factor MYC3
4yz6_A	6e-19	5	202	2	192	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	382	387	ERRRRE
2	383	388	RRRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcriptional activator. Control tissue-specific synthesis of anthocyanin pigments in various parts of the maize plant.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	ORGLA04G0183800.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK111704	0.0	AK111704.1 Oryza sativa Japonica Group cDNA clone:J023013E24, full insert sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015635094.1	0.0	anthocyanin regulatory R-S protein
Swissprot	P13027	1e-176	ARRS_MAIZE; Anthocyanin regulatory R-S protein
TrEMBL	I1PNR9	0.0	I1PNR9_ORYGL; Uncharacterized protein
STRING	ORGLA04G0183800.1	0.0	(Oryza glaberrima)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP932	33	109

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	5e-85	bHLH family protein

Publications ? help Back to Top
Pattanaik S,Xie CH,Yuan L The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength. Planta, 2008. 227(3): p. 707-15 [PMID:18075757] Huang ZA, et al. The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.). J Genet Genomics, 2012. 39(3): p. 149-56 [PMID:22464474] Perrot GH,Cone KC Nucleotide sequence of the maize R-S gene. Nucleic Acids Res., 1989. 17(19): p. 8003 [PMID:2798145] Li P, et al. Combined bulked segregant sequencing and traditional linkage analysis for identification of candidate gene for purple leaf sheath in maize. PLoS ONE, 2018. 13(1): p. e0190670 [PMID:29304111]