PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

OB12G13530.1

Organism

Oryza brachyantha

Taxonomic ID

4533

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza

Family

E2F/DP

Protein Properties

Length: 403aa MW: 44310.8 Da PI: 4.359

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
OB12G13530.1	genome	OGE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	83.5	1.7e-26	87	152	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kfl+ll+ ++ giv+ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg OB12G13530.1 87 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 152 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	7.3E-28	85	153	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.5E-16	87	150	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	8.6E-35	87	152	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.5E-23	89	152	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.63E-49	163	269	No hit	No description
SuperFamily	SSF144074	6.54E-34	164	269	No hit	No description
Pfam	PF16421	3.3E-34	168	267	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005667	Cellular Component	transcription factor complex
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 403 aa Download sequence Send to blast
MTEAVLVRTP LKRKHDREEN EAAESNDWMM SPGYANAAGS PVPTPLSGKG SKAFAKSKAA 60 KGQKSCPQTP LCASSPGNPA TPVGGCRYDS SLGLLTKKFL NLLKGAPGGI VDLNNAAETL 120 EVQKRRIYDI TNVLEGIGLI EKKLKNNIRW KGIDDSRPGE VSDDMSILRA DIEALSLQEH 180 SLDQQISEMR DKLRGLTEDE NNQKWLYVTE DDIKSLPCFQ NQTLIAIKAP HGTTLEVPDP 240 DEVNDYPQRR YRIVLRSTMG PIDVYLVSQF EEMSGMETPP RTVQTVSMDS LENPMTPLAA 300 ESNKAAETEP NIQDGLLMPS DAPSSSQDIG GMMKIVPSEL DTDADYWLLS DTGVSITDMW 360 KTAPEVEWEG IEKFNAEDFL EVSTPRQQDK PSSDIMDGDS CVS

Sequence ? help Back to Top

Protein Sequence Length: 403 aa Download sequence Send to blast

MTEAVLVRTP LKRKHDREEN EAAESNDWMM SPGYANAAGS PVPTPLSGKG SKAFAKSKAA  60
KGQKSCPQTP LCASSPGNPA TPVGGCRYDS SLGLLTKKFL NLLKGAPGGI VDLNNAAETL  120
EVQKRRIYDI TNVLEGIGLI EKKLKNNIRW KGIDDSRPGE VSDDMSILRA DIEALSLQEH  180
SLDQQISEMR DKLRGLTEDE NNQKWLYVTE DDIKSLPCFQ NQTLIAIKAP HGTTLEVPDP  240
DEVNDYPQRR YRIVLRSTMG PIDVYLVSQF EEMSGMETPP RTVQTVSMDS LENPMTPLAA  300
ESNKAAETEP NIQDGLLMPS DAPSSSQDIG GMMKIVPSEL DTDADYWLLS DTGVSITDMW  360
KTAPEVEWEG IEKFNAEDFL EVSTPRQQDK PSSDIMDGDS CVS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	4e-23	79	153	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	OB12G13530.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK059233	0.0	AK059233.1 Oryza sativa Japonica Group cDNA clone:001-024-E10, full insert sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015698223.1	0.0	PREDICTED: transcription factor E2FA-like
Swissprot	Q9FNY0	1e-120	E2FA_ARATH; Transcription factor E2FA
TrEMBL	J3NBJ5	0.0	J3NBJ5_ORYBR; Uncharacterized protein
STRING	OB12G13530.1	0.0	(Oryza brachyantha)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-106	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]