PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 512aa MW: 56043.3 Da PI: 8.9896

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf10465g02005.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	90	112	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Niben101Scf10465g02005.1 90 FVCEICNKGFQRDQNLQLHRRGH 112 89*******************88 PP
2	zf-C2H2	12.3	0.00052	166	188	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H +t+ Niben101Scf10465g02005.1 166 WKCDKCSKKYAVQSDWKAHHKTC 188 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.7E-5	89	112	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.34E-6	89	112	No hit	No description
SMART	SM00355	0.017	90	112	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	90	112	IPR007087	Zinc finger, C2H2
Pfam	PF12171	8.2E-5	90	112	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	92	112	IPR007087	Zinc finger, C2H2
SMART	SM00355	130	131	161	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.8E-4	154	187	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.34E-6	161	186	No hit	No description
SMART	SM00355	130	166	186	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 512 aa Download sequence Send to blast
MSNISGEGGS FSSGNTGEEE VEKHNQAAAH LKTSNNISSI TSNGSSSQSQ QQQNKQQPLA 60 KKKRNLPGTP DPNAEVIALS PTTLMATNRF VCEICNKGFQ RDQNLQLHRR GHNLPWKLRQ 120 RSTTEVRKRV YICPESTCVH HCPARALGDL TGIKKHYSRK HGEKKWKCDK CSKKYAVQSD 180 WKAHHKTCGT REYKCDCGTI FSRRDSFITH RAFCDALAEE NNKVKQGVTN NNTEPNLQSG 240 QMLGLMSSNA SLGLSDFNNF DPKTPLKSLP QDLLPIPFKS MNNNMAAGAM FSTTSGSLFG 300 SPRSVASSSS GLQSNFNYLQ DTSKNGAGQG QAPMSATALL QKAAQMGATA SSSINSPMMQ 360 KSFVTSGAMA GPYVSPSLYE NFQTQPDNNT NNHQLNLAAV MNDMGMYSGI LMSNDHQNIN 420 TEHDQENNIN TNDSSSVRNQ STVLGHNGNN DMLTVDFLGV GGSSRPPSLH EQQRLEAAIN 480 QQRMQASAIN PFHQQNISHG NNSAMEKPIW DI

Sequence ? help Back to Top

Protein Sequence Length: 512 aa Download sequence Send to blast

MSNISGEGGS FSSGNTGEEE VEKHNQAAAH LKTSNNISSI TSNGSSSQSQ QQQNKQQPLA  60
KKKRNLPGTP DPNAEVIALS PTTLMATNRF VCEICNKGFQ RDQNLQLHRR GHNLPWKLRQ  120
RSTTEVRKRV YICPESTCVH HCPARALGDL TGIKKHYSRK HGEKKWKCDK CSKKYAVQSD  180
WKAHHKTCGT REYKCDCGTI FSRRDSFITH RAFCDALAEE NNKVKQGVTN NNTEPNLQSG  240
QMLGLMSSNA SLGLSDFNNF DPKTPLKSLP QDLLPIPFKS MNNNMAAGAM FSTTSGSLFG  300
SPRSVASSSS GLQSNFNYLQ DTSKNGAGQG QAPMSATALL QKAAQMGATA SSSINSPMMQ  360
KSFVTSGAMA GPYVSPSLYE NFQTQPDNNT NNHQLNLAAV MNDMGMYSGI LMSNDHQNIN  420
TEHDQENNIN TNDSSSVRNQ STVLGHNGNN DMLTVDFLGV GGSSRPPSLH EQQRLEAAIN  480
QQRMQASAIN PFHQQNISHG NNSAMEKPIW DI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	7e-34	162	232	3	72	Zinc finger protein JACKDAW
5b3h_F	7e-34	162	232	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019239150.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-112	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A1J6JXR1	0.0	A0A1J6JXR1_NICAT; Zinc finger protein jackdaw
STRING	XP_009620710.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-101	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]