PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf09489g00001.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 371aa    MW: 42412.2 Da    PI: 6.7889
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf09489g00001.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.40.0009879101323
                               ET..TTTEEESSHHHHHHHHHHT CS
                   zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                               C+   Cgk+F +   L++H   H
  Niben101Scf09489g00001.1  79 CSydSCGKTFIDAGALRKHSHIH 101
                               77779**************7766 PP
2zf-C2H216.52.4e-05106130123
                               EEET..TTTEEESSHHHHHHHHHHT CS
                   zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                               y+C+   Cgk F ++s LkrH   H
  Niben101Scf09489g00001.1 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                               9********************8877 PP
3zf-C2H222.43.2e-07136160123
                               EEET..TTTEEESSHHHHHHHHHHT CS
                   zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                               y+Cp   Cgk Fs   nL++H++tH
  Niben101Scf09489g00001.1 136 YVCPheGCGKAFSLDFNLRSHMKTH 160
                               99**********************9 PP
4zf-C2H214.30.00012166191123
                               EEET..TTTEEESSHHHHHHHHHH.T CS
                   zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                               + Cp   Cgk++ + + Lk+H  + H
  Niben101Scf09489g00001.1 166 HICPypECGKRYAHEYKLKNHVASsH 191
                               679999***************99888 PP
5zf-C2H216.13.1e-05229254123
                               EEET..TTTEEESSHHHHHHHHHH.T CS
                   zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                               y+Cp   C+ks+ + + L+ H+r+ H
  Niben101Scf09489g00001.1 229 YSCPyeGCDKSYIHEYKLNLHLRNmH 254
                               99*********************988 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.8E-1272103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.03277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.03277106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.06E-880130No hitNo description
Gene3DG3DSA:3.30.160.602.3E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576671.59E-14117170No hitNo description
Gene3DG3DSA:3.30.160.603.6E-20127162IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.882136165IPR007087Zinc finger, C2H2
SMARTSM003551.7E-4136160IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.5E-7163187IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.286166196IPR007087Zinc finger, C2H2
SMARTSM003550.032166191IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.1E-9223251IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.57E-5223251No hitNo description
PROSITE profilePS5015711.344229259IPR007087Zinc finger, C2H2
SMARTSM003558.2E-4229254IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 371 aa     Download sequence    Send to blast
MEIHMAHHLF ERRPIYKSKA PASKWFKEWV PQDVVATGGK CYLLKWVNEA TLKALKEKPK  60
EPEVPLPEPE PTTEVLFLCS YDSCGKTFID AGALRKHSHI HGERQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDYVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PECGKRYAHE  180
YKLKNHVASS HQKNSTPDAP KYTPPVEKPM KTPKSSSAAY ASSSSDRPYS CPYEGCDKSY  240
IHEYKLNLHL RNMHPGHFPE DNAKNVQSTA DNEMDEGSDQ DAYAAKRGNG KIQKHSRPKP  300
SLKQPPLKVA RKSSSASPAN ISMAPKKPWP VKEENYNEED SEETEEERDD VGDGWRYGEN  360
DDDDEETEED E
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-32791898119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019229384.10.0PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-156YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A314KMZ60.0A0A314KMZ6_NICAT; Putative zinc finger protein
STRINGXP_009768399.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA73432332
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-144C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]