PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 278aa MW: 31467.4 Da PI: 6.7503

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf09456g00019.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.1	3.5e-19	119	173	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ ++tkeq +Le+ F+++++++ +++ LAk+lgLt rqV vWFqNrRa+ k Niben101Scf09456g00019.1 119 RKKLRLTKEQSAVLEDNFKEHSTLNPKQKLALAKRLGLTARQVEVWFQNRRARTK 173 678899***********************************************98 PP
2	HD-ZIP_I/II	123.1	1.4e-39	119	208	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeve 85 +kk+rl+keq+++LE++F+e+++L+p++K +la++Lgl++rqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rL+kev+ Niben101Scf09456g00019.1 119 RKKLRLTKEQSAVLEDNFKEHSTLNPKQKLALAKRLGLTARQVEVWFQNRRARTKLKQTEVDCEFLKRCVENLTEENSRLQKEVQ 203 69********************************************************************************* PP HD-ZIP_I/II 86 eLreel 91 eLr +l Niben101Scf09456g00019.1 204 ELR-AL 208 9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	1.8E-26	2	93	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	8.98E-19	108	176	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.281	115	175	IPR001356	Homeobox domain
SMART	SM00389	1.0E-16	117	179	IPR001356	Homeobox domain
Pfam	PF00046	1.2E-16	119	173	IPR001356	Homeobox domain
CDD	cd00086	1.51E-15	119	176	No hit	No description
Gene3D	G3DSA:1.10.10.60	7.2E-18	119	171	IPR009057	Homeodomain-like
PRINTS	PR00031	1.0E-5	146	155	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	150	173	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.0E-5	155	171	IPR000047	Helix-turn-helix motif
Gene3D	G3DSA:1.20.5.170	2.7E-4	172	207	No hit	No description
Pfam	PF02183	8.4E-10	175	209	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	8.1E-26	175	218	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010582	Biological Process	floral meristem determinacy
GO:0048467	Biological Process	gynoecium development
GO:0080127	Biological Process	fruit septum development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MEDLGLSLSL SFPQNMTDSF PVHLNLDRKT SWTDSFPSSD RNSETCRVET KTFLKGIDVN 60 QLPATADAEE EAGVSSPNST ISSVSGNKRN DREPNCEEHE MERACSRGIS DEEDGETCRK 120 KLRLTKEQSA VLEDNFKEHS TLNPKQKLAL AKRLGLTARQ VEVWFQNRRA RTKLKQTEVD 180 CEFLKRCVEN LTEENSRLQK EVQELRALKL SPQFYMQMIP PTTLTMCPSC ERVASGPTST 240 PVNLRLGPPR QLNLWTTTPI SQGQFGQIDS YPTLARQK

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	167	175	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00050	PBM	Transfer from AT4G17460	Download

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019228499.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT4-like isoform X1
Swissprot	P46600	4e-98	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	A0A314KNB1	0.0	A0A314KNB1_NICAT; Homeobox-leucine zipper protein hat4
STRING	XP_009788263.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G16780.1	3e-95	homeobox protein 2

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]