PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Niben101Scf07825g04013.1

Organism

Nicotiana benthamiana

Taxonomic ID

4100

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

NAC

Protein Properties

Length: 294aa MW: 34743.9 Da PI: 8.3698

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf07825g04013.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	153.8	7.9e-48	61	186	2	128
NAM 2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWka 85 ppG+rF P+deel+ +yLkk+v +++l+ + i+ev++yk+ P++L + ++kewyfF++rd+ky++g+r+nra+ +gyWka Niben101Scf07825g04013.1 61 PPGYRFCPHDEELIIHYLKKRVMNERLPH-DKINEVNLYKYTPQELSeNYSMLGDKEWYFFTPRDRKYPNGNRPNRAAGTGYWKA 144 9************************99.88**********844444599************************** PP NAM 86 tgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 tg dk++++ ++ +vg +k Lvfy+g+ pkg kt+W+mhe+r+ Niben101Scf07825g04013.1 145 TGADKPIKH-NDIKVGFRKALVFYEGKPPKGDKTNWIMHEFRV 186 *****.999**************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.31E-57	51	212	IPR003441	NAC domain
PROSITE profile	PS51005	55.048	60	212	IPR003441	NAC domain
Pfam	PF02365	3.1E-25	61	186	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 294 aa Download sequence Send to blast
MEFDEQTKAH LTANSQNPKI QEQEKQKQVE AEKGLIIVKS NYNSISEISR VNYVDDSFVF 60 PPGYRFCPHD EELIIHYLKK RVMNERLPHD KINEVNLYKY TPQELSENYS MLGDKEWYFF 120 TPRDRKYPNG NRPNRAAGTG YWKATGADKP IKHNDIKVGF RKALVFYEGK PPKGDKTNWI 180 MHEFRVNESR RLKRHAKDMR LDDWVLCRIY KKVDKSFKNA RKEQEQDDTS ISYSSIGKME 240 NCDYEGTTDS YEIARQNLTL PHRYDITSDD PGFNMDYNKY SLDNISHYGP ISNY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	6e-59	60	212	15	168	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that positively regulates age-dependent senescence, dark-induced leaf senescence and stress-induced senescence. Regulates leaf senescence through the modulation of the expression of senescence-associated genes SGR1/NYE1, SAG113 and SAUR36/SAG201, which are involved in chlorophyll degradation, and abscisic acid (ABA) and auxin promotion of senescence, respectively. Promotes reactive oxygen species (ROS) production during age-dependent and stress-induced senescence. Regulates positively auxin-mediated responses in roots (PubMed:27388337). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269\|PubMed:18849494, ECO:0000269\|PubMed:26518251, ECO:0000269\|PubMed:27388337}.
UniProt	Transcription factor of the NAC family associated with male fertility. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) (PubMed:26518251). Induced by salinity and osmotic stress, and during leaf senescence (PubMed:27388337). {ECO:0000269\|PubMed:26518251, ECO:0000269\|PubMed:27388337}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019223930.1	0.0	PREDICTED: NAC transcription factor 29-like
Swissprot	A2YMR0	4e-63	NAC10_ORYSI; NAC transcription factor ONAC010
Swissprot	Q9CAR0	1e-63	NAC32_ARATH; NAC transcription factor 32
TrEMBL	A0A314KX34	0.0	A0A314KX34_NICAT; Nac transcription factor nam-b1
STRING	XP_009759087.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA746	24	103

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G77450.1	2e-65	NAC domain containing protein 32

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Takasaki H, et al. SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence. Plant J., 2015. 84(6): p. 1114-23 [PMID:26518251] Mahmood K,El-Kereamy A,Kim SH,Nambara E,Rothstein SJ ANAC032 Positively Regulates Age-Dependent and Stress-Induced Senescence in Arabidopsis thaliana. Plant Cell Physiol., 2016. 57(10): p. 2029-2046 [PMID:27388337] Allu AD,Brotman Y,Xue GP,Balazadeh S Transcription factor ANAC032 modulates JA/SA signalling in response to Pseudomonas syringae infection. EMBO Rep., 2016. 17(11): p. 1578-1589 [PMID:27632992] Mahmood K,Xu Z,El-Kereamy A,Casaretto JA,Rothstein SJ The Arabidopsis Transcription Factor ANAC032 Represses Anthocyanin Biosynthesis in Response to High Sucrose and Oxidative and Abiotic Stresses. Front Plant Sci, 2016. 7: p. 1548 [PMID:27790239] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239]