PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 184aa MW: 20819.2 Da PI: 9.0927

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf06518g02008.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.8	9.2e-09	123	163	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +Av+Y+k L Niben101Scf06518g02008.1 123 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAVHYVKFL 163 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.345	114	163	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	7.2E-14	115	173	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.57E-14	118	173	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.0E-13	120	169	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.0E-6	124	163	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.93E-6	137	168	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 184 aa Download sequence Send to blast
MDLQDIAQSL ELGFSSSNIE MIPLQPQVHK YSNYLMTSPP SNFSFMGNPI EEPNIPIISS 60 IIASAHSSGN EYSCLQNTNS MEAMREMIFR MAMMQPIHID PLSVKPPKRK NVKISKDPQS 120 VAARHRRERI SERIRILQRL VPGGTKMDTA SMLDEAVHYV KFLKKQLQSL EQAAILKYGI 180 CTVE

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009799029.1	1e-109	PREDICTED: transcription factor HEC1-like
Refseq	XP_016488611.1	1e-109	PREDICTED: transcription factor HEC1-like
Swissprot	Q9SND4	6e-48	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A1S4BIC1	1e-108	A0A1S4BIC1_TOBAC; transcription factor HEC1-like
TrEMBL	A0A1U7YIF2	1e-108	A0A1U7YIF2_NICSY; transcription factor HEC1-like
STRING	XP_009799029.1	1e-109	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	2e-44	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]