PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

AP2

Protein Properties

Length: 389aa MW: 44296.5 Da PI: 9.3458

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf05173g05003.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.4	1.5e-17	103	153	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIr p k +r +lg++ t+e+Aa a+++a+ k++g Niben101Scf05173g05003.1 103 RYRGVRRRP-WGKFAAEIRNP---DrKGARLWLGTYETPEDAALAYDQAAYKIRG 153 7******.******8...3245***********************98 PP
2	AP2	61.8	1.5e-19	295	345	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrdp + k++r +lg++ t+e+Aa a+++a+ k++g Niben101Scf05173g05003.1 295 RYRGVRRRP-WGKFAAEIRDP---NkKNARLWLGTYETPEDAALAYDQAAFKIRG 345 8******.******9...5467***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	2.8E-13	103	153	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.302	103	161	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.68E-22	103	162	IPR016177	DNA-binding domain
CDD	cd00018	7.55E-29	103	163	No hit	No description
SMART	SM00380	1.8E-35	103	167	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.3E-31	103	162	IPR001471	AP2/ERF domain
CDD	cd00018	4.43E-30	294	355	No hit	No description
Pfam	PF00847	2.2E-14	295	345	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.15E-23	295	354	IPR016177	DNA-binding domain
PROSITE profile	PS51032	24.605	295	353	IPR001471	AP2/ERF domain
SMART	SM00380	8.3E-39	295	359	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.8E-32	295	354	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.3E-13	296	307	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.3E-13	335	355	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 389 aa Download sequence Send to blast
MYEQTTISDS DLSVLENIKF HLLNDTDFSQ IFSMFDQCFN NAEIINSPNS SYGSSPTEEF 60 SWGDMLTSIN SSWVQVDKLE HKEEAKEKHV VARGVHASQD WNRYRGVRRR PWGKFAAEIR 120 NPDRKGARLW LGTYETPEDA ALAYDQAAYK IRGSKARLNF PHLIGSNISE PVRVAPRRRC 180 LLPEISSSPF SLSFVENKKR REKMNSADLS LLESIQHHLL NDSNIPEIFS AMDSNSPSSS 240 FSNSPSTENN FYYGELTPLI NPTLVATEKS HEFEETNNKE TVSARVAKAP QDWKRYRGVR 300 RRPWGKFAAE IRDPNKKNAR LWLGTYETPE DAALAYDQAA FKIRGSKARL NFPHLVGSGM 360 PEPARVNPRR RSHSPEPSSE NGTPRKLFV

Sequence ? help Back to Top

Protein Sequence Length: 389 aa Download sequence Send to blast

MYEQTTISDS DLSVLENIKF HLLNDTDFSQ IFSMFDQCFN NAEIINSPNS SYGSSPTEEF  60
SWGDMLTSIN SSWVQVDKLE HKEEAKEKHV VARGVHASQD WNRYRGVRRR PWGKFAAEIR  120
NPDRKGARLW LGTYETPEDA ALAYDQAAYK IRGSKARLNF PHLIGSNISE PVRVAPRRRC  180
LLPEISSSPF SLSFVENKKR REKMNSADLS LLESIQHHLL NDSNIPEIFS AMDSNSPSSS  240
FSNSPSTENN FYYGELTPLI NPTLVATEKS HEFEETNNKE TVSARVAKAP QDWKRYRGVR  300
RRPWGKFAAE IRDPNKKNAR LWLGTYETPE DAALAYDQAA FKIRGSKARL NFPHLVGSGM  360
PEPARVNPRR RSHSPEPSSE NGTPRKLFV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	1e-27	104	359	4	69	ATERF1
3gcc_A	1e-27	104	359	4	69	ATERF1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	196	203	NKKRREKM
2	197	202	KKRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:11950980}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Strongly induced by wounding. Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1, but seems to not be affected by ethylene. Induction by salicylic acid (SA) is controlled by growth and/or developmental conditions, and seems to be more efficient and independent of PAD4 in older plants. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12068110}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009593489.1	1e-126	PREDICTED: ethylene-responsive transcription factor 13-like
Refseq	XP_016511096.1	1e-126	PREDICTED: ethylene-responsive transcription factor 13-like
Swissprot	Q8L9K1	2e-40	ERF99_ARATH; Ethylene-responsive transcription factor 13
TrEMBL	S0BAP4	1e-125	S0BAP4_TOBAC; Ethylene response factor 163
STRING	XP_009593489.1	1e-126	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44840.1	2e-41	ethylene-responsive element binding factor 13

Publications ? help Back to Top
Maimbo M,Ohnishi K,Hikichi Y,Yoshioka H,Kiba A Induction of a small heat shock protein and its functional roles in Nicotiana plants in the defense response against Ralstonia solanacearum. Plant Physiol., 2007. 145(4): p. 1588-99 [PMID:17965181] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]