PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

NAC

Protein Properties

Length: 476aa MW: 54421.2 Da PI: 6.5507

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf04217g02012.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	96.6	3.7e-30	5	79	54	129
NAM 54 eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrle 129 e+++wyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++s k+ l+g++ktLv+ykgrap+g+k+d +mheyrle Niben101Scf04217g02012.1 5 EQSDWYFFSHKDKKYPTGTRTNRATAAGFWKATGRDKAIYS-KHDLIGMRKTLVYYKGRAPNGQKSDFIMHEYRLE 79 5679***********************************.8899**************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	37.151	1	98	IPR003441	NAC domain
SuperFamily	SSF101941	2.48E-34	6	98	IPR003441	NAC domain
Pfam	PF02365	2.6E-13	8	78	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 476 aa Download sequence Send to blast
MGTEEQSDWY FFSHKDKKYP TGTRTNRATA AGFWKATGRD KAIYSKHDLI GMRKTLVYYK 60 GRAPNGQKSD FIMHEYRLET DPNGAPQARW VICRVFKKKI AAMRMDTSEH GSPIWYDDQL 120 SFMPDNMDSP KPQYPHSNTI TNYNHRYPNN YPNCKKELDN LHYQIPPHQQ FLQLPLLQTN 180 TKHLAAAPPG ISCSSMPIFG INVNQEHMHP TFGNNINRGC TNDQVEDQVT DWRVLDKFVA 240 SQLSQEDENN YSNARGNDSN SRVKVSDKQE MAPENTSTAS SSSQIDLWNE HGSPIWYDDQ 300 LSFMPDNMDS PKPQYPHSNT IINYNHNYPN NYPNCKKELD NLHYQISPHH QNQQFLQLPL 360 LETNSKLLAA APPGISCSSM PIFGINVNQE HMHPTFGNNL NRGCINDQVE DQVTDWRVLD 420 KFVASQLSQE DENNYSNAAN ARGDNSNLKV KNLDKQELAP ENTSTASSSS QIDLWK

Sequence ? help Back to Top

Protein Sequence Length: 476 aa Download sequence Send to blast

MGTEEQSDWY FFSHKDKKYP TGTRTNRATA AGFWKATGRD KAIYSKHDLI GMRKTLVYYK  60
GRAPNGQKSD FIMHEYRLET DPNGAPQARW VICRVFKKKI AAMRMDTSEH GSPIWYDDQL  120
SFMPDNMDSP KPQYPHSNTI TNYNHRYPNN YPNCKKELDN LHYQIPPHQQ FLQLPLLQTN  180
TKHLAAAPPG ISCSSMPIFG INVNQEHMHP TFGNNINRGC TNDQVEDQVT DWRVLDKFVA  240
SQLSQEDENN YSNARGNDSN SRVKVSDKQE MAPENTSTAS SSSQIDLWNE HGSPIWYDDQ  300
LSFMPDNMDS PKPQYPHSNT IINYNHNYPN NYPNCKKELD NLHYQISPHH QNQQFLQLPL  360
LETNSKLLAA APPGISCSSM PIFGINVNQE HMHPTFGNNL NRGCINDQVE DQVTDWRVLD  420
KFVASQLSQE DENNYSNAAN ARGDNSNLKV KNLDKQELAP ENTSTASSSS QIDLWK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-26	6	104	70	171	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-26	6	104	70	171	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-26	6	104	70	171	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-26	6	104	70	171	NO APICAL MERISTEM PROTEIN
4dul_A	1e-26	6	104	70	171	NAC domain-containing protein 19
4dul_B	1e-26	6	104	70	171	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:16103214, PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019234679.1	0.0	PREDICTED: NAC domain-containing protein 7-like
Swissprot	Q9FWX2	2e-83	NAC7_ARATH; NAC domain-containing protein 7
TrEMBL	A0A1J6K906	0.0	A0A1J6K906_NICAT; Nac domain-containing protein 7
STRING	XP_009602844.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA134	24	297

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12260.1	2e-71	NAC 007

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469]