PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 183aa MW: 20532.7 Da PI: 10.4888

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf03000g02009.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.1	7.7e-09	92	132	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Niben101Scf03000g02009.1 92 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYMKFL 132 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.894	83	132	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.7E-14	88	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.4E-13	88	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.1E-14	89	138	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.4E-6	93	132	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.39E-7	106	137	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 183 aa Download sequence Send to blast
MLDYHNSHTF FNAPASTISF TGSPSIIQHQ ETLRNTVGAY PSHTVKRNSM AAMREMIFKI 60 AAMQPIQIDP ESVKPPKRKN VKISNDPQSV AARHRRERIS ERIRILQRLV PGGTKMDTAS 120 MLDEAIHYMK FLKKQVQSLE KVEATRPIAA ASGCLGFPVP MSSLSGNYLP MGSKTYYPYH 180 QSV

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009766851.1	1e-122	PREDICTED: transcription factor HEC2-like
Refseq	XP_016456456.1	1e-122	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	4e-47	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A1S3YVV6	1e-121	A0A1S3YVV6_TOBAC; transcription factor HEC2-like
TrEMBL	A0A1U7VPH1	1e-121	A0A1U7VPH1_NICSY; transcription factor HEC2-like
STRING	XP_009766851.1	1e-121	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	2e-43	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]