PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 512aa MW: 56405.7 Da PI: 9.2476

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf02042g03032.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	92	114	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Niben101Scf02042g03032.1 92 FVCEICNKGFQRDQNLQLHRRGH 114 89*******************88 PP
2	zf-C2H2	15.6	4.6e-05	168	190	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ Niben101Scf02042g03032.1 168 WKCDKCSKKYAVQSDWKAHQKTC 190 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.7E-5	91	114	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.32E-8	91	114	No hit	No description
PROSITE profile	PS50157	10.949	92	114	IPR007087	Zinc finger, C2H2
Pfam	PF12171	8.2E-5	92	114	IPR022755	Zinc finger, double-stranded RNA binding
SMART	SM00355	0.017	92	114	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	94	114	IPR007087	Zinc finger, C2H2
SMART	SM00355	77	133	163	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.8E-5	156	189	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.32E-8	163	189	No hit	No description
SMART	SM00355	94	168	188	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 512 aa Download sequence Send to blast
MSNISGEEGS FSSGNTGDQQ VQKHNQAAYL KTSNNISSSI TTTSNGSTSQ FQQQQNKQQP 60 LAKKRRNLPG TPDPNAEVIA LSPTTLMATN RFVCEICNKG FQRDQNLQLH RRGHNLPWKL 120 RQRSTTEVRK RVYICPEPTC VHHNPARALG DLTGIKKHYS RKHGEKKWKC DKCSKKYAVQ 180 SDWKAHQKTC GTREYKCDCG TIFSRRDSFI THRAFCDALA EENNKVNQGL RNNNMEPNLQ 240 SGQMHGLMSS NASLGLSDFN NFDPKTSLKS LPQELLPIPF KCMNNNMAAG AMFSTASGNL 300 FGSPRSVASS SSGLQSNFNY LQDSSKNGAG QGQAPMSATA LLQKAAQMGA TASSSINSPM 360 MQKSFVTSAM AGPYVSPSLY ENFQTQPDNN TNNHQPNLAA VMNDMGMYSG ILMSNDHQDI 420 NTEHHQENNN TNDSSSVRNQ STVLGHNGNN DMLTVDFLGV GGSSRPPSLH EQQRLEAAIN 480 QQRMQASAIN PFHQQNISHG NNSAMEKPIW DI

Sequence ? help Back to Top

Protein Sequence Length: 512 aa Download sequence Send to blast

MSNISGEEGS FSSGNTGDQQ VQKHNQAAYL KTSNNISSSI TTTSNGSTSQ FQQQQNKQQP  60
LAKKRRNLPG TPDPNAEVIA LSPTTLMATN RFVCEICNKG FQRDQNLQLH RRGHNLPWKL  120
RQRSTTEVRK RVYICPEPTC VHHNPARALG DLTGIKKHYS RKHGEKKWKC DKCSKKYAVQ  180
SDWKAHQKTC GTREYKCDCG TIFSRRDSFI THRAFCDALA EENNKVNQGL RNNNMEPNLQ  240
SGQMHGLMSS NASLGLSDFN NFDPKTSLKS LPQELLPIPF KCMNNNMAAG AMFSTASGNL  300
FGSPRSVASS SSGLQSNFNY LQDSSKNGAG QGQAPMSATA LLQKAAQMGA TASSSINSPM  360
MQKSFVTSAM AGPYVSPSLY ENFQTQPDNN TNNHQPNLAA VMNDMGMYSG ILMSNDHQDI  420
NTEHHQENNN TNDSSSVRNQ STVLGHNGNN DMLTVDFLGV GGSSRPPSLH EQQRLEAAIN  480
QQRMQASAIN PFHQQNISHG NNSAMEKPIW DI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-34	164	234	3	72	Zinc finger protein JACKDAW
5b3h_F	2e-34	164	234	3	72	Zinc finger protein JACKDAW
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019239150.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-112	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A1J6JXR1	0.0	A0A1J6JXR1_NICAT; Zinc finger protein jackdaw
STRING	XP_009620710.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-101	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]