PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf01571g03004.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family HD-ZIP
Protein Properties Length: 717aa    MW: 79256.1 Da    PI: 6.5063
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf01571g03004.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox60.72.4e-192677556
                              SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                  Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                              +++t++q+++Le+lF+++++p++++r +L++ lgL  rq+k+WFqNrR++ k
  Niben101Scf01571g03004.1 26 HRHTAHQIQRLEALFKECPHPDEQSRLQLSRDLGLAPRQIKFWFQNRRTQLK 77
                              689*********************************************9987 PP
2START1749.4e-552234482206
                               HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT- CS
                     START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetl 76 
                               +a  a++e +++ + +ep+W+ks     + ++ d + ++f+++++       ++ea+r+sgvv+m+   lv+ ++d++ +W e +
  Niben101Scf01571g03004.1 223 IASNAMEEWIRLLQTDEPLWTKSTtdgrDVLDLDSYNKIFPRANSslknsnVRTEASRDSGVVIMNGLALVNMFMDVN-KWMEFF 306
                               67889********************99999999*******9999999999999*************************.****** PP

                               S....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSE CS
                     START  77 a....kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpS 150
                               +    ka t+evis g      ++lqlm+ e+q+lsplvp R++ f+R+++q  +g+w+ivdvS d  q+++  ss+  +++lpS
  Niben101Scf01571g03004.1 307 PtivsKARTIEVISCGviggqsSTLQLMYEEMQVLSPLVPtRESFFLRFCKQIDQGSWAIVDVSYDIIQENQYPSSSCMVHRLPS 391
                               ****************************************************************9999999886667779***** PP

                               EEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                     START 151 giliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                               g+li++++ng+skvtwvehv+++++   h l+r l++sg+a+ga +w+  lqr+ce+
  Niben101Scf01571g03004.1 392 GCLIQDMPNGYSKVTWVEHVEVEEKGLiHKLYRDLIHSGMAFGAERWLGSLQRLCER 448
                               **********************987555***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466894.14E-19779IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.606.6E-21873IPR009057Homeodomain-like
PROSITE profilePS5007117.3461979IPR001356Homeobox domain
SMARTSM003892.3E-182083IPR001356Homeobox domain
CDDcd000865.39E-182180No hitNo description
PfamPF000465.6E-172677IPR001356Homeobox domain
PROSITE patternPS0002705477IPR017970Homeobox, conserved site
PROSITE profilePS5084846.999213451IPR002913START domain
SuperFamilySSF559611.8E-37214450No hitNo description
CDDcd088751.79E-112217447No hitNo description
SMARTSM002343.7E-44222448IPR002913START domain
PfamPF018521.1E-46223448IPR002913START domain
Gene3DG3DSA:3.30.530.201.7E-5331438IPR023393START-like domain
SuperFamilySSF559617.5E-20469682No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 717 aa     Download sequence    Send to blast
MEYCGVTSSS GGGDGSETHR KKKRFHRHTA HQIQRLEALF KECPHPDEQS RLQLSRDLGL  60
APRQIKFWFQ NRRTQLKSQH ERADNCALRA ENDRIRCENI AIKEAIKNVI CPSCGGPPVT  120
EDSYFDEQKL RMENMQLKEE LDKISSIAAK YIGRPISQLP PVQPIHLSSL NLMSMSSFGG  180
IGLTGPSLDL DLLPVNSMSS TIPSLPFPTL NISDMDKTLM ADIASNAMEE WIRLLQTDEP  240
LWTKSTTDGR DVLDLDSYNK IFPRANSSLK NSNVRTEASR DSGVVIMNGL ALVNMFMDVN  300
KWMEFFPTIV SKARTIEVIS CGVIGGQSST LQLMYEEMQV LSPLVPTRES FFLRFCKQID  360
QGSWAIVDVS YDIIQENQYP SSSCMVHRLP SGCLIQDMPN GYSKVTWVEH VEVEEKGLIH  420
KLYRDLIHSG MAFGAERWLG SLQRLCERYA CLMVSGKSSR ELGGVIPSPE GKMSMMKLAQ  480
RMVSNFCASI NPSNGHQWSN ISGLDEFEVR ATLQKSTDPG QPNGVIISAA STIWLPVPSQ  540
HVFNFLRDER ARPQWDVLSN QNPVQEVAHI ANGSHPGNCI SVLRAYNTGQ NNMLILQESC  600
IDSSGSLVIY SPVDLPSINM AMSGEDTTYV PLLPSGFTIS PDGRQGQRSN KASCSSTNSG  660
TMGDNGSEGS LVTVVFQILV SSLSSSAKMS PESVNTVNNL IGNTIHQIKA ALNCSTS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016451582.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A1S3YI130.0A0A1S3YI13_TOBAC; homeobox-leucine zipper protein HDG11-like
STRINGXP_009778533.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]