PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 269aa MW: 30542.2 Da PI: 7.5382

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf01500g01020.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	58.5	1.1e-18	117	171	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++k+q +Lee F+++++++ +++ LAk+lgL rqV vWFqNrRa+ k Niben101Scf01500g01020.1 117 RKKLRLSKDQSAILEETFKEHNTLNPKQKLALAKRLGLRPRQVEVWFQNRRARTK 171 788899***********************************************98 PP
2	HD-ZIP_I/II	128.4	3e-41	117	206	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeve 85 +kk+rlsk+q+++LEe+F+e+++L+p++K +la++Lgl+prqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rL+kev+ Niben101Scf01500g01020.1 117 RKKLRLSKDQSAILEETFKEHNTLNPKQKLALAKRLGLRPRQVEVWFQNRRARTKLKQTEVDCEFLKRCCENLTEENRRLQKEVQ 201 69********************************************************************************* PP HD-ZIP_I/II 86 eLreel 91 eLr +l Niben101Scf01500g01020.1 202 ELR-AL 206 9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	1.5E-18	2	95	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	2.34E-18	109	174	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.313	113	173	IPR001356	Homeobox domain
SMART	SM00389	7.4E-16	115	177	IPR001356	Homeobox domain
Pfam	PF00046	3.8E-16	117	171	IPR001356	Homeobox domain
CDD	cd00086	2.17E-15	117	174	No hit	No description
Gene3D	G3DSA:1.10.10.60	7.6E-18	122	171	IPR009057	Homeodomain-like
PRINTS	PR00031	2.5E-5	144	153	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	148	171	IPR017970	Homeobox, conserved site
PRINTS	PR00031	2.5E-5	153	169	IPR000047	Helix-turn-helix motif
Pfam	PF02183	2.0E-11	173	207	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	4.2E-27	173	216	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009641	Biological Process	shade avoidance
GO:0009734	Biological Process	auxin-activated signaling pathway
GO:0009826	Biological Process	unidimensional cell growth
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 269 aa Download sequence Send to blast
MMVEKEDLGL SLSLSFPDNN NKTSTTTNNP FHHQLNLIPS SSPFNLFHKT SWTDSFSSSD 60 VNRLPATADA DEEAGVSSPN STISSVSGNK RSERETNNCE EHEMERASDE EDGETSRKKL 120 RLSKDQSAIL EETFKEHNTL NPKQKLALAK RLGLRPRQVE VWFQNRRART KLKQTEVDCE 180 FLKRCCENLT EENRRLQKEV QELRALKLSP QFYMQMTPPT TLTMCPSCER VGGPPTSSDP 240 TSTHVGPAQH RPMPFNLWAN TPKSLHLRS

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	115	121	SRKKLRL
2	165	173	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that plays a role in auxin-mediated morphogenesis. Negatively regulates lateral root elongation. {ECO:0000269\|PubMed:12492842}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00550	DAP	Transfer from AT5G47370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By indole-3-acetic acid (IAA). {ECO:0000269\|PubMed:12492842}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019224375.1	1e-178	PREDICTED: homeobox-leucine zipper protein HAT4
Swissprot	P46601	1e-100	HAT2_ARATH; Homeobox-leucine zipper protein HAT2
TrEMBL	A0A314KVI8	1e-176	A0A314KVI8_NICAT; Homeobox-leucine zipper protein hat4
STRING	XP_009589459.1	1e-176	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G16780.1	2e-98	homeobox protein 2

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697]