PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

TALE

Protein Properties

Length: 147aa MW: 16808.2 Da PI: 9.8342

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf00650g06001.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	28.8	2.1e-09	100	133	22	55
SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS Homeobox 22 nrypsaeereeLAkklgLterqVkvWFqNrRake 55 +yp++ ++ LA+++gL+ +q+ +WF N+R ++ Niben101Scf00650g06001.1 100 WPYPTEGDKNSLAESTGLDPKQINNWFINQRKRH 133 58*****************************985 PP
2	ELK	32.7	1.6e-11	53	74	1	22
ELK 1 ELKhqLlrKYsgyLgsLkqEFs 22 ELK++LlrK++++L+sLk EFs Niben101Scf00650g06001.1 53 ELKDRLLRKFGSHLSSLKLEFS 74 9********************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03789	4.4E-8	53	74	IPR005539	ELK domain
PROSITE profile	PS51213	10.196	53	73	IPR005539	ELK domain
SMART	SM01188	8.4E-6	53	74	IPR005539	ELK domain
PROSITE profile	PS50071	12.617	73	136	IPR001356	Homeobox domain
SuperFamily	SSF46689	7.7E-20	74	143	IPR009057	Homeodomain-like
SMART	SM00389	1.0E-12	75	140	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	9.9E-29	78	137	IPR009057	Homeodomain-like
CDD	cd00086	2.63E-11	85	137	No hit	No description
Pfam	PF05920	5.1E-18	93	132	IPR008422	Homeobox KN domain
PROSITE pattern	PS00027	0	111	134	IPR017970	Homeobox, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 147 aa Download sequence Send to blast
MTLGVCRILR KGCILADPAG AVTILRSPND GGVSSDEELS CGEAEGQRNE DNELKDRLLR 60 KFGSHLSSLK LEFSKKKKKG KLPKQARQML LAWWNDHYRW PYPTEGDKNS LAESTGLDPK 120 QINNWFINQR KRHWKPSENM QLAVMDN

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269\|PubMed:16798887}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269\|PubMed:11311158, ECO:0000269\|PubMed:16798887}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016490194.1	2e-73	PREDICTED: homeobox protein knotted-1-like 6
Swissprot	Q84JS6	1e-53	KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBL	A0A1S4BMV4	4e-72	A0A1S4BMV4_TOBAC; homeobox protein knotted-1-like 6
STRING	XP_009759718.1	2e-70	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA753	24	80

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G23380.1	2e-45	KNOTTED1-like homeobox gene 6

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]