PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Niben101Scf00052g04001.1

Organism

Nicotiana benthamiana

Taxonomic ID

4100

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 376aa MW: 41673.3 Da PI: 7.1962

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf00052g04001.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	20	1.9e-06	155	176	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C Cgk F+r nL+ H+r H Niben101Scf00052g04001.1 155 FCDFCGKGFKRDANLRMHMRAH 176 6*******************99 PP
2	zf-C2H2	12.1	0.00058	240	263	1	23
EEETTTT.EEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCg.ksFsrksnLkrHirtH 23 y+C+ C+ ksFs +Lk+H++ + Niben101Scf00052g04001.1 240 YSCTRCNnKSFSVLADLKSHLKHC 263 99*******************977 PP
3	zf-C2H2	11.8	0.00075	271	287	5	21
TTTEEESSHHHHHHHHH CS zf-C2H2 5 dCgksFsrksnLkrHir 21 Cg+sFsrk+ L H+ Niben101Scf00052g04001.1 271 SCGTSFSRKDKLFGHMA 287 5**************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.99E-6	151	177	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.7E-6	154	176	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	12.092	154	181	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0024	154	176	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	156	176	IPR007087	Zinc finger, C2H2
SMART	SM00355	150	202	235	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	13	240	262	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	210	268	292	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 376 aa Download sequence Send to blast
MSFLGDLRHT PAQTKPPLTT ISAAASIIGD DPRVPLLNLS AVQARMDTLQ KFLSDSVNSN 60 TLLGQHQMKM VSDEITSAIH QIIVNGAALL SSTQSTNHPP QLPELKINPK PNHKRTFSEF 120 DRRGSEVEVL EEEDGDGLEI IELDAVELLA EHIHFCDFCG KGFKRDANLR MHMRAHGNQY 180 KTPEALAKPD KCIDSGSKNR KFSCPFVGCC RNKSHSKFRP LKSAICVKNH FKRSHCPKMY 240 SCTRCNNKSF SVLADLKSHL KHCGETKWKC SCGTSFSRKD KLFGHMALFE GHMPAIEPEE 300 EAKPPSPAAV EDDVKMDVSG SDNGFLDLRI GSDKGFLDRL MVDAFESIDS YCFQDLLGSS 360 SPNGSNTVPG TNEWFS

Sequence ? help Back to Top

Protein Sequence Length: 376 aa Download sequence Send to blast

MSFLGDLRHT PAQTKPPLTT ISAAASIIGD DPRVPLLNLS AVQARMDTLQ KFLSDSVNSN  60
TLLGQHQMKM VSDEITSAIH QIIVNGAALL SSTQSTNHPP QLPELKINPK PNHKRTFSEF  120
DRRGSEVEVL EEEDGDGLEI IELDAVELLA EHIHFCDFCG KGFKRDANLR MHMRAHGNQY  180
KTPEALAKPD KCIDSGSKNR KFSCPFVGCC RNKSHSKFRP LKSAICVKNH FKRSHCPKMY  240
SCTRCNNKSF SVLADLKSHL KHCGETKWKC SCGTSFSRKD KLFGHMALFE GHMPAIEPEE  300
EAKPPSPAAV EDDVKMDVSG SDNGFLDLRI GSDKGFLDRL MVDAFESIDS YCFQDLLGSS  360
SPNGSNTVPG TNEWFS

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019234243.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Swissprot	Q9C8N5	4e-81	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A1J6K9Z7	0.0	A0A1J6K9Z7_NICAT; Protein sensitive to proton rhizotoxicity 1
STRING	XP_009626824.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA10000	21	26

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.3	6e-71	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]