PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_9515_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family AP2
Protein Properties Length: 426aa    MW: 46287.1 Da    PI: 5.3374
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_9515_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP241.43.5e-13179229155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s+y+GV+ +k  grW+A+   +     +k+++lg f+++ eAa+a+++a+ k +g
  Neem_9515_f_1 179 SKYRGVTLHK-CGRWEARMGQF--L-GKKYIYLGLFDSEVEAARAYDKAAIKCNG 229
                    89********.7******5553..2.26**********99**********99776 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS510329.6980144IPR001471AP2/ERF domain
SMARTSM003804.4E-5105150IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.8E-8115144IPR001471AP2/ERF domain
SuperFamilySSF541716.21E-6115144IPR016177DNA-binding domain
SuperFamilySSF541716.54E-17179238IPR016177DNA-binding domain
CDDcd000182.38E-26179239No hitNo description
PfamPF008471.1E-8179229IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.108.7E-16180237IPR001471AP2/ERF domain
SMARTSM003802.5E-32180243IPR001471AP2/ERF domain
PROSITE profilePS5103215.527180237IPR001471AP2/ERF domain
PRINTSPR003674.1E-6181192IPR001471AP2/ERF domain
PRINTSPR003674.1E-6219239IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
MLDLNLNVVS IESTQQNSDE RVGSVLLLEK SPEGSSGTSN SSVVNADASS NVGDDESCST  60
RAVAGDSSVY TFNFDILKVG DRNGKNKDKY ENDGELRREF AFFPVTGGAN GRDGGGFDTA  120
HAAARAYDRA AIKFRGVDAD INFSLADYEE DMKQMKNLTK EEFVHILRRQ STGFSRGSSK  180
YRGVTLHKCG RWEARMGQFL GKKYIYLGLF DSEVEAARAY DKAAIKCNGR EAVTNFEPST  240
YEGEINSEGS NEAGEHNLDL NLGISPTSGS GPKENEGHPQ FLSGPYGVYA GRNSMMENFN  300
AAAAGDSPSK GLMRTSEHPR FWNGVYPSFL RTEERATEKR IELGPQQSLP NWAWQMHGQV  360
SATSMPLFST AASSGFSFPA TPPSAAVLSS KPINPTALNL CFTSSTTAAP NTSQLFYQMK  420
PPQEPP
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
UniProtProbable transcription factor (By similarity). Involved in spikelet transition. Regulator of starch biosynthesis especially during seed development (e.g. endosperm starch granules); represses the expression of type I starch synthesis genes. Prevents lemma and palea elongation as well as grain growth (By similarity). {ECO:0000250|UniProtKB:P47927, ECO:0000250|UniProtKB:Q2TQ34}.
UniProtProbable transcription factor (By similarity). Involved in spikelet transition. Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes. Prevents lemma and palea elongation as well as grain growth. Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (By similarity). {ECO:0000250|UniProtKB:P47927, ECO:0000250|UniProtKB:Q8H443}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00615PBMTransfer from AT2G28550Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749, ECO:0000305|PubMed:28066457}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAM4379186e-97AM437918.1 Vitis vinifera contig VV78X091249.7, whole genome shotgun sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006488203.11e-178ethylene-responsive transcription factor RAP2-7 isoform X1
SwissprotB8AXC35e-82AP21_ORYSI; APETALA2-like protein 1
SwissprotB8B8J27e-83AP23_ORYSI; APETALA2-like protein 3
SwissprotQ8H4437e-83AP23_ORYSJ; APETALA2-like protein 3
TrEMBLA0A2H5NED61e-177A0A2H5NED6_CITUN; Uncharacterized protein
STRINGXP_006488203.11e-177(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58612747
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G28550.33e-93related to AP2.7
Publications ? help Back to Top
  1. Lee DY,An G
    Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice.
    Plant J., 2012. 69(3): p. 445-61
    [PMID:22003982]
  2. Wang L, et al.
    Coordinated regulation of vegetative and reproductive branching in rice.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9
    [PMID:26631749]
  3. Dai Z,Wang J,Zhu M,Miao X,Shi Z
    OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice.
    Front Plant Sci, 2016. 7: p. 1891
    [PMID:28066457]