PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

C2H2

Protein Properties

Length: 489aa MW: 50853.2 Da PI: 9.427

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_8211_f_2	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.3	1.4e-05	61	83	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Neem_8211_f_2 61 FVCEICNKGFQRDQNLQLHRRGH 83 89*******************88 PP
2	zf-C2H2	17.2	1.4e-05	137	159	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ C+k + +s+ k H++t+ Neem_8211_f_2 137 YKCERCSKKYAVQSDWKAHMKTC 159 9********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.38E-8	60	83	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	60	83	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	61	83	IPR007087	Zinc finger, C2H2
Pfam	PF12171	7.8E-5	61	83	IPR022755	Zinc finger, double-stranded RNA binding
SMART	SM00355	0.017	61	83	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	63	83	IPR007087	Zinc finger, C2H2
SMART	SM00355	89	102	132	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.2E-6	125	158	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.38E-8	132	158	No hit	No description
PROSITE profile	PS50157	8.517	137	165	IPR007087	Zinc finger, C2H2
SMART	SM00355	43	137	157	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 489 aa Download sequence Send to blast
MTVSTATGEA SVSSPGSQIE MIPLSAAPPP QKKKRNLPGM PDPDSLVIAL SPKTLLATNR 60 FVCEICNKGF QRDQNLQLHR RGHNLPWKLK QRNSKEIRKK VYVCPEPTCV HHNPARALGD 120 LTGIKKHFSR KHGEKKYKCE RCSKKYAVQS DWKAHMKTCG TREYKCDCGT IFSRRDSFIT 180 HRAFCDALAE ESARAQTLPV ASREENPNAK TVASPPPPPL TPSTGVVSPG LSIQSSEMPA 240 ENPMGLSPPR SVATTTSAST STTTSVFASV FSSSAISQPS QTPATSSFSN QISALARSDC 300 PSSGCGIEPT SLSLSPSLYL SNNSCSLFSK ADQSHIHYAP SPQPAMSATA LLQKAAQIGA 360 TSSTPSYLRG LGLAVSSSSS GQAGNGKQEN NSASAAGGLG LGLSSGLTDG VMDPSSLFGS 420 KPTTLDLLGL GIGAGGASTS GLSALLTSFG GGFNVGGSSI SYGGGRESSP GGEPWEGAPE 480 RKPNGPALP

Sequence ? help Back to Top

Protein Sequence Length: 489 aa Download sequence Send to blast

MTVSTATGEA SVSSPGSQIE MIPLSAAPPP QKKKRNLPGM PDPDSLVIAL SPKTLLATNR  60
FVCEICNKGF QRDQNLQLHR RGHNLPWKLK QRNSKEIRKK VYVCPEPTCV HHNPARALGD  120
LTGIKKHFSR KHGEKKYKCE RCSKKYAVQS DWKAHMKTCG TREYKCDCGT IFSRRDSFIT  180
HRAFCDALAE ESARAQTLPV ASREENPNAK TVASPPPPPL TPSTGVVSPG LSIQSSEMPA  240
ENPMGLSPPR SVATTTSAST STTTSVFASV FSSSAISQPS QTPATSSFSN QISALARSDC  300
PSSGCGIEPT SLSLSPSLYL SNNSCSLFSK ADQSHIHYAP SPQPAMSATA LLQKAAQIGA  360
TSSTPSYLRG LGLAVSSSSS GQAGNGKQEN NSASAAGGLG LGLSSGLTDG VMDPSSLFGS  420
KPTTLDLLGL GIGAGGASTS GLSALLTSFG GGFNVGGSSI SYGGGRESSP GGEPWEGAPE  480
RKPNGPALP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	7e-36	133	198	3	68	Zinc finger protein JACKDAW
5b3h_F	7e-36	133	198	3	68	Zinc finger protein JACKDAW
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	87	99	KLKQRNSKEIRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269\|PubMed:21571950, ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006473474.1	0.0	protein indeterminate-domain 2-like
Swissprot	Q9LVQ7	1e-139	IDD1_ARATH; Zinc finger protein ENHYDROUS
TrEMBL	A0A2H5NSM9	0.0	A0A2H5NSM9_CITUN; Uncharacterized protein
STRING	XP_006473473.1	0.0	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM155	28	306

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-113	C2H2-like zinc finger protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]