PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_4530_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family NAC
Protein Properties Length: 577aa    MW: 64668.6 Da    PI: 5.1242
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_4530_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM170.26.5e-53742051128
            NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevls 94 
                    lp GfrF+Ptdeel+++yL+ k++g++ e+ evi+e+d++k+ePwdLp  + +k+++ ew+fF++rd+ky++g r+nrat++gyWkatgkd+++ s
  Neem_4530_f_1  74 LPLGFRFRPTDEELINHYLRLKINGRDSEV-EVIPEIDVCKWEPWDLPglSVIKTDDPEWFFFCPRDRKYPNGLRSNRATDAGYWKATGKDRTIRS 168
                    699************************999.99***************6447888899************************************** PP

            NAM  95 k...kgelvglkktLvfykgrapkgektdWvmheyrl 128
                    +   +++ +g+kktLvfy+grapkge+t+W+mheyr+
  Neem_4530_f_1 169 RksgSNNCIGMKKTLVFYRGRAPKGERTNWIMHEYRA 205
                    96655566***************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019417.32E-6263228IPR003441NAC domain
PROSITE profilePS5100558.75674228IPR003441NAC domain
PfamPF023651.2E-2775204IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0071470Biological Processcellular response to osmotic stress
GO:1900426Biological Processpositive regulation of defense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005516Molecular Functioncalmodulin binding
Sequence ? help Back to Top
Protein Sequence    Length: 577 aa     Download sequence    Send to blast
MSRDQSVLRN GIPAQERRSK AGESRALCFK QLKRPFITKR DSTRRGVQKA TRFGHEMLTC  60
RKCNTMTVLS VESLPLGFRF RPTDEELINH YLRLKINGRD SEVEVIPEID VCKWEPWDLP  120
GLSVIKTDDP EWFFFCPRDR KYPNGLRSNR ATDAGYWKAT GKDRTIRSRK SGSNNCIGMK  180
KTLVFYRGRA PKGERTNWIM HEYRATDKDL QVTKPGQAAF VLCRLFRKPE EKNDVEAQQT  240
ESPDMTKSSP DDTSSDLVQE TPISDYECPG VGENPYQYEL PSNGEIDCKI FSPMQSNPDL  300
GSLDGTNEQD VSLSDLLDEV FNNHDEFSCE ESNGQKELAI ETKMQLPGEI YMSQTISSEN  360
FHVKDNSTFS VTDTGVAQLQ HRDLAMGSSG WFNDHLESKG SFGGYGDNSG TQLSSSNNSA  420
MGSFCGNFNN YDLSTTLKNP VDNSGDFAGG TGIKIRTRQP QHRPNSFNSV TQGTAPGRLR  480
LQTELSSAPV GTGEQKDVSL SKEEDEVQSV VTEIDEPAEQ SQTSDGESQV LELDETKELT  540
QEASTKLRLR VKRDGEIWHS QDGAISVKRG TDCTSWK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-456922812165NO APICAL MERISTEM PROTEIN
1ut4_B1e-456922812165NO APICAL MERISTEM PROTEIN
1ut7_A1e-456922812165NO APICAL MERISTEM PROTEIN
1ut7_B1e-456922812165NO APICAL MERISTEM PROTEIN
4dul_A1e-456922812165NAC domain-containing protein 19
4dul_B1e-456922812165NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:18443413, PubMed:24329768). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites (PubMed:17947243). Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene (PubMed:22826500). Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression (PubMed:24329768). Mediates osmotic stress signaling in leaf senescence by up-regulating senescence-associated genes (PubMed:18443413). {ECO:0000269|PubMed:17947243, ECO:0000269|PubMed:18443413, ECO:0000269|PubMed:22826500, ECO:0000269|PubMed:24329768}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00108PBMTransfer from AT4G35580Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006439176.10.0protein NTM1-like 9
SwissprotF4JN351e-128NTL9_ARATH; Protein NTM1-like 9
TrEMBLV4TR990.0V4TR99_9ROSI; Uncharacterized protein
STRINGXP_006439176.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM55942848
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G35580.21e-130NAC transcription factor-like 9
Publications ? help Back to Top
  1. Zheng XY, et al.
    Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(30): p. 9166-73
    [PMID:26139525]
  2. Guo T, et al.
    Lamin-like Proteins Negatively Regulate Plant Immunity through NAC WITH TRANSMEMBRANE MOTIF1-LIKE9 and NONEXPRESSOR OF PR GENES1 in Arabidopsis thaliana.
    Mol Plant, 2017. 10(10): p. 1334-1348
    [PMID:28943325]