PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

C2H2

Protein Properties

Length: 223aa MW: 24238.7 Da PI: 9.9274

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_41267_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.8	0.00017	26	48	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H Neem_41267_f_1 26 FSCNYCQRKFYSSQALGGHQNAH 48 89******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	9.1E-7	23	53	No hit	No description
PROSITE profile	PS50157	11.427	26	53	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	28	48	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 223 aa Download sequence Send to blast
MANSSQTSSE TPQASSDHHH AEQRVFSCNY CQRKFYSSQA LGGHQNAHKR ERTLAKRGQR 60 IGTYTTAAAA AASAIAFGQP YLHQNHFSSI SSLPLHGAYN RSLGIQVHSM IHKPNHLSSS 120 HGNGNIYGHN SWSRPPIDQQ PAIGRLSAME TFHANPAATT SSRASVGRFN IVRSTMGSSS 180 PADHIEATSN CWWEGGGRSN SDSGGMRITN QEELQKLDLS LKL

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. Involved in the regulation of vegetative development and fertility. Modulates red light signaling in seedling photomorphogenesis. {ECO:0000269\|PubMed:24808098}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by abscisic acid (ABA). {ECO:0000269\|PubMed:24808098}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006450313.1	1e-108	zinc finger protein 3
Refseq	XP_006483451.1	1e-108	zinc finger protein 3-like
Swissprot	Q39262	7e-48	ZFP3_ARATH; Zinc finger protein 3
TrEMBL	A0A2H5NW01	1e-107	A0A2H5NW01_CITUN; Uncharacterized protein
TrEMBL	V4TSL2	1e-107	V4TSL2_9ROSI; Uncharacterized protein
STRING	XP_006483451.1	1e-108	(Citrus sinensis)
STRING	XP_006450313.1	1e-108	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1893	27	71

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G25160.1	8e-47	zinc finger protein 3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Zhang A, et al. The Arabidopsis Gene zinc finger protein 3(ZFP3) Is Involved in Salt Stress and Osmotic Stress Response. PLoS ONE, 2016. 11(12): p. e0168367 [PMID:27977750]