PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_4048_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family TALE
Protein Properties Length: 304aa    MW: 33332.2 Da    PI: 8.7705
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_4048_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox27.55.5e-091081382454
                    S--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS
       Homeobox  24 ypsaeereeLAkklgLterqVkvWFqNrRak 54 
                    yp+ +e+  LAk++gL+ +qV++WF N R +
  Neem_4048_f_1 108 YPTDTEKLMLAKQTGLSRSQVSNWFINARVR 138
                    9****************************88 PP
2BELL64.32.6e-211433072
           BELL 30 lqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72
                   +q+v++sFe vaglg+a+pY++lAlka+S+hFrcLk+ai++q+
  Neem_4048_f_1  1 MQAVVASFEYVAGLGNAAPYANLALKAMSKHFRCLKNAITDQL 43
                   9***************************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF075263.5E-16140IPR006563POX domain
SMARTSM003897.2E-790146IPR001356Homeobox domain
CDDcd000866.59E-1190143No hitNo description
Gene3DG3DSA:1.10.10.601.1E-1790149IPR009057Homeodomain-like
SuperFamilySSF466891.92E-12106148IPR009057Homeodomain-like
PfamPF059201.8E-13107138IPR008422Homeobox KN domain
PROSITE profilePS5007111.094108142IPR001356Homeobox domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010076Biological Processmaintenance of floral meristem identity
GO:0010077Biological Processmaintenance of inflorescence meristem identity
GO:0010089Biological Processxylem development
GO:0010154Biological Processfruit development
GO:0010223Biological Processsecondary shoot formation
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048457Biological Processfloral whorl morphogenesis
GO:0048645Biological Processorgan formation
GO:0080006Biological Processinternode patterning
GO:0005634Cellular Componentnucleus
GO:0005829Cellular Componentcytosol
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 304 aa     Download sequence    Send to blast
MQAVVASFEY VAGLGNAAPY ANLALKAMSK HFRCLKNAIT DQLQFSNKAQ VQSNCGKDEA  60
STFGSTDRVP YGQRPVHNSG FIERPSQPVW RPQRGLPERA VTVLRACYPT DTEKLMLAKQ  120
TGLSRSQVSN WFINARVRLW KPMVEEIHTL ETRQAQKVSQ NEERSANRSN DHLHSSNSFP  180
SENPSTSTPT LQDTPSKRTR NEFPTIPVGN EEPANLSYNS LSNHQHLGVG VSMAGGSSGV  240
SLTLGLYQNH GIGLSEAYPI SAAQRFGLGL EGNNEGYVLS GYEAQNRIFG RDVIGGQLLH  300
DFVG
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989, ECO:0000269|PubMed:15120075, ECO:0000269|PubMed:15155890, ECO:0000269|PubMed:16741748}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006429214.10.0BEL1-like homeodomain protein 9
RefseqXP_006480898.10.0BEL1-like homeodomain protein 9
SwissprotQ9LZM82e-74BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBLA0A067EVK50.0A0A067EVK5_CITSI; Uncharacterized protein
TrEMBLA0A2H5PBN90.0A0A2H5PBN9_CITUN; Uncharacterized protein
TrEMBLV4USB60.0V4USB6_9ROSI; Uncharacterized protein
STRINGXP_006480898.10.0(Citrus sinensis)
STRINGXP_006429214.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM56882746
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G35940.34e-46BEL1-like homeodomain 1
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]
  4. Andrés F, et al.
    Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE.
    Plant Physiol., 2015. 169(3): p. 2187-99
    [PMID:26417007]
  5. Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R
    Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis.
    Dev. Cell, 2016. 39(2): p. 198-208
    [PMID:27666746]
  6. Sehra B,Franks RG
    Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development.
    Front Plant Sci, 2017. 8: p. 1712
    [PMID:29085379]
  7. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]