PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

HB-other

Protein Properties

Length: 133aa MW: 15925.4 Da PI: 10.3483

Description

HB-other family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_30993_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.3	7.3e-20	19	77	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le+++ ++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ Neem_30993_f_1 19 KYVRYTPEQVEALERVYSECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 77 6789*****************************************************97 PP
2	bZIP_1	22.6	2.3e-07	71	113	18	60
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 18 rrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklk 60 rr+R++ ++e +L++ +L+a Nk L +e+++l+k+v+ l Neem_30993_f_1 71 RRCREKQRKEASRLQTVNRKLSAMNKLLMEENDRLQKQVSHLV 113 9**************************************9875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.694	14	78	IPR001356	Homeobox domain
SMART	SM00389	4.4E-15	16	82	IPR001356	Homeobox domain
CDD	cd00086	1.67E-12	19	79	No hit	No description
SuperFamily	SSF46689	8.13E-18	19	82	IPR009057	Homeodomain-like
Pfam	PF00046	2.0E-17	19	77	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	7.8E-20	21	74	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.20.5.170	7.7E-4	75	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 133 aa Download sequence Send to blast
MALAIHNKEL ANKQMDSSKY VRYTPEQVEA LERVYSECPK PSSLRRQQLI RECPILSNIE 60 PKQIKVWFQN RRCREKQRKE ASRLQTVNRK LSAMNKLLME ENDRLQKQVS HLVYENGYMR 120 QQLHSVSLYI FSK

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. {ECO:0000269\|PubMed:11395776, ECO:0000269\|PubMed:15328016, ECO:0000269\|PubMed:15598805}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by miR165 and miR166. {ECO:0000269\|PubMed:14999284, ECO:0000269\|PubMed:16033795, ECO:0000269\|PubMed:17237362}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY919619	4e-50	AY919619.1 Populus trichocarpa class III HD-Zip protein 4 (HB4) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024047817.1	3e-79	homeobox-leucine zipper protein ATHB-14 isoform X2
Swissprot	O04291	6e-71	ATB14_ARATH; Homeobox-leucine zipper protein ATHB-14
TrEMBL	A0A2H5N204	1e-77	A0A2H5N204_CITUN; Uncharacterized protein
STRING	XP_006468302.1	3e-78	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM18074	5	9

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G34710.1	3e-73	HD-ZIP family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Müller CJ, et al. PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis. Plant Physiol., 2016. 170(2): p. 956-70 [PMID:26637548] Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules. Development, 2016. 143(3): p. 422-6 [PMID:26700684] Kim ES, et al. HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots. Physiol Plant, 2016. 157(2): p. 221-33 [PMID:26968317] Husbands AY,Aggarwal V,Ha T,Timmermans MC In Planta Single-Molecule Pull-Down Reveals Tetrameric Stoichiometry of HD-ZIPIII:LITTLE ZIPPER Complexes. Plant Cell, 2016. 28(8): p. 1783-94 [PMID:27385814] Di Ruocco G, et al. Differential spatial distribution of miR165/6 determines variability in plant root anatomy. Development, 2018. [PMID:29158439] Wójcik AM,Nodine MD,Gaj MD miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis. Front Plant Sci, 2017. 8: p. 2024 [PMID:29321785] Hashimoto K,Miyashima S,Sato-Nara K,Yamada T,Nakajima K Functionally Diversified Members of the MIR165/6 Gene Family Regulate Ovule Morphogenesis in Arabidopsis thaliana. Plant Cell Physiol., 2018. 59(5): p. 1017-1026 [PMID:29462472]