PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

C2H2

Protein Properties

Length: 255aa MW: 28358.7 Da PI: 10.4795

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_30031_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.4	6e-06	61	83	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Neem_30031_f_1 61 FVCEICNKGFQRDQNLQLHRRGH 83 89*******************88 PP
2	zf-C2H2	18.3	6.3e-06	137	159	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ C+k + +s+ k H++t+ Neem_30031_f_1 137 YKCERCSKKYAVQSDWKAHMKTC 159 9********************98 PP
3	zf-C2H2	10.6	0.0017	167	185	5	23
TTTEEESSHHHHHHHHHHT CS zf-C2H2 5 dCgksFsrksnLkrHirtH 23 dCg+ Fsr++++ +H + Neem_30031_f_1 167 DCGTIFSRRDSFITHRAFC 185 8**************8765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	7.22E-9	60	83	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.0E-6	60	83	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	3.4E-5	61	83	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.949	61	83	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	61	83	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	63	83	IPR007087	Zinc finger, C2H2
SMART	SM00355	89	102	132	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.9E-6	125	158	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.22E-9	132	158	No hit	No description
PROSITE profile	PS50157	8.517	137	165	IPR007087	Zinc finger, C2H2
SMART	SM00355	43	137	157	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 255 aa Download sequence Send to blast
MTVSTATGEA SVSSPGSQIE MIPLSAAPPP QKKKRNLPGM PDPDSLVIAL SPKTLLATNR 60 FVCEICNKGF QRDQNLQLHR RGHNLPWKLK QRNSKEIRKK VYVCPEPTCV HHNPARALGD 120 LTGIKKHFSR KHGEKKYKCE RCSKKYAVQS DWKAHMKTCG TREYKCDCGT IFSRRDSFIT 180 HRAFCDALAE ESARAQTLPV ASREENPNAK TVASPPPPPL TPSTGVVSPG LSIQSSESIS 240 SKIKKKLRGY RERTP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	5e-37	133	199	3	69	Zinc finger protein JACKDAW
5b3h_F	5e-37	133	199	3	69	Zinc finger protein JACKDAW
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	87	99	KLKQRNSKEIRKK
2	241	247	KIKKKLR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269\|PubMed:21571950, ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006473474.1	1e-142	protein indeterminate-domain 2-like
Swissprot	Q9LVQ7	1e-113	IDD1_ARATH; Zinc finger protein ENHYDROUS
TrEMBL	A0A067H9P5	1e-141	A0A067H9P5_CITSI; Uncharacterized protein
TrEMBL	A0A1U8JB63	1e-140	A0A1U8JB63_GOSHI; protein indeterminate-domain 2-like
STRING	XP_006473473.1	1e-141	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM155	28	306

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-115	C2H2-like zinc finger protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]