PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

HB-other

Protein Properties

Length: 193aa MW: 21842.2 Da PI: 9.0202

Description

HB-other family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_27295_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.8	4.9e-20	27	85	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le+l++++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ Neem_27295_f_1 27 KYVRYTPEQVEALERLYHECPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 85 5679*****************************************************97 PP
2	bZIP_1	20.1	1.4e-06	79	121	18	60
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 18 rrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklk 60 rr+R++ ++e +L+ +L+a Nk L +e+++l+k+v++l Neem_27295_f_1 79 RRCREKQRKEASRLQAVNRKLTAMNKLLMEENDRLQKQVSQLA 121 9***************************************996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.661	22	86	IPR001356	Homeobox domain
SMART	SM00389	5.3E-16	24	90	IPR001356	Homeobox domain
SuperFamily	SSF46689	3.94E-18	26	90	IPR009057	Homeodomain-like
CDD	cd00086	3.68E-16	27	87	No hit	No description
Pfam	PF00046	1.2E-17	28	85	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.1E-19	29	82	IPR009057	Homeodomain-like
CDD	cd14686	2.85E-5	79	118	No hit	No description
Gene3D	G3DSA:1.20.5.170	5.9E-4	83	123	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 193 aa Download sequence Send to blast
MSFSLAEMMA VSSGCKDSNK MVMDNGKYVR YTPEQVEALE RLYHECPKPS SMRRQQLIRE 60 CPILSNIEPK QIKVWFQNRR CREKQRKEAS RLQAVNRKLT AMNKLLMEEN DRLQKQVSQL 120 ATLATTDTSC ESVVTSGQHH LTPQHPPRDA SPAGLLSIAE ETLTEFLSKA TGTAVEWVQM 180 PGMKVSAVST IIF

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269\|PubMed:11402194, ECO:0000269\|PubMed:15598805}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by miR165. {ECO:0000269\|PubMed:17237362, ECO:0000269\|PubMed:8575317}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AM453607	3e-74	AM453607.2 Vitis vinifera contig VV78X179473.2, whole genome shotgun sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009378434.1	1e-115	PREDICTED: homeobox-leucine zipper protein ATHB-15-like, partial
Refseq	XP_022729737.1	1e-114	homeobox-leucine zipper protein ATHB-8 isoform X1
Swissprot	Q39123	1e-103	ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBL	A0A061GKU3	1e-113	A0A061GKU3_THECC; Class III HD-Zip protein 8 isoform 2 (Fragment)
TrEMBL	A0A0D2UGF7	1e-113	A0A0D2UGF7_GOSRA; Uncharacterized protein
STRING	XP_009378434.1	1e-114	(Pyrus x bretschneideri)
STRING	EOY29771	1e-113	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM18074	5	9

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G32880.1	1e-106	homeobox gene 8

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis. Planta, 2014. 239(5): p. 989-1001 [PMID:24488524] Baima S, et al. Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module. Mol Plant, 2014. 7(6): p. 1006-1025 [PMID:24777988] Kakehi J, et al. Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana. PLoS ONE, 2015. 10(1): p. e0117309 [PMID:25625317] Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Liu S, et al. Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis. Front Plant Sci, 2015. 6: p. 388 [PMID:26082787] Yamaguchi YL, et al. Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots. Front Plant Sci, 2017. 8: p. 1195 [PMID:28747918] Yamazaki K, et al. Suppression of DELLA signaling induces procambial cell formation in culture. Plant J., 2018. 94(1): p. 48-59 [PMID:29383774]