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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Neem_25150_f_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
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Family | E2F/DP | ||||||||
Protein Properties | Length: 462aa MW: 51673.3 Da PI: 5.5803 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.6 | 1.9e-27 | 161 | 226 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Neem_25150_f_1 161 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 226 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.9E-29 | 158 | 228 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 9.2E-35 | 161 | 226 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.99E-17 | 161 | 224 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.6E-24 | 163 | 226 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 2.85E-36 | 237 | 316 | No hit | No description |
SuperFamily | SSF144074 | 1.07E-27 | 239 | 327 | No hit | No description |
Pfam | PF16421 | 2.1E-25 | 242 | 325 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 462 aa Download sequence Send to blast |
MSNSQTPQDN PSQQSFKRQL PFSSMKPPFL APGDYHRFAA EPRRRSDQEV EAIVVKSPGI 60 GLVRLVIKIS CWGLDLVKFW SWRQLKRKND PADLEAESSE RATGPGYTEI VNSPLQTPVS 120 GKGGKAQKTS RLTKNNKSGP QISSANLGSP GSNLTPTGPC RYDSSLGLLT KKFINLIKHA 180 EDGILDLNKA ADTLEVQKRR IYDITNVLEG IGLIEKKLKN RIQWKGLDVS RPGEVDENAS 240 SLQAEVESLT VEERRLDEQI RVMQERLRDL SEDESNQKWL FVTEDDIKSL PCFQNETLIA 300 IKAPHGTTLE VPDPDEVQFL LVNSTNHLNQ FSDASHSVII SRHSSQFEEK FEEIHGAEAP 360 PNLPSTSGFN ENPAATMIME ESGGKEIEMQ EQDAQTICTD LNSSQDFVSG IMKIVPSEVD 420 KDRICSVTGN FVFISTSSVL YFSRYLKLIR GRMSLKNELF FK |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-26 | 156 | 227 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006424133.1 | 0.0 | transcription factor E2FB isoform X1 | ||||
Swissprot | Q9FV71 | 1e-133 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | V4RS35 | 0.0 | V4RS35_9ROSI; Uncharacterized protein | ||||
STRING | XP_006424133.1 | 0.0 | (Citrus clementina) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.3 | 1e-135 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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