PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_1522_f_5
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family MYB_related
Protein Properties Length: 314aa    MW: 34031 Da    PI: 10.1868
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_1522_f_5genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding42.81.2e-1396140347
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      +WT+eE+ l++ + ++ G+g+W+ I+r + k+Rt+ q+ s+ qky
    Neem_1522_f_5  96 PWTEEEHRLFLLGLQKVGKGDWRGISRNFVKTRTPTQVASHAQKY 140
                      7*******************************************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS501588.647520IPR001878Zinc finger, CCHC-type
PROSITE profilePS5129416.39589145IPR017930Myb domain
SuperFamilySSF466891.12E-1691143IPR009057Homeodomain-like
TIGRFAMsTIGR015574.9E-1792143IPR006447Myb domain, plants
SMARTSM007171.5E-993143IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.3E-1196140IPR009057Homeodomain-like
PfamPF002499.6E-1196140IPR001005SANT/Myb domain
CDDcd001671.81E-996141No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009733Biological Processresponse to auxin
GO:0009737Biological Processresponse to abscisic acid
GO:0009739Biological Processresponse to gibberellin
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0031540Biological Processregulation of anthocyanin biosynthetic process
GO:0046686Biological Processresponse to cadmium ion
GO:0080167Biological Processresponse to karrikin
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003682Molecular Functionchromatin binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 314 aa     Download sequence    Send to blast
MSRSCSQCGN NGHNSRTCAE AAGGGGSCGS GSSAENGIML FGVRVTEGGS SFRKSVSMNN  60
LSQFDQPQDS NAEAGYASDD VVHASGRSRE RKRGIPWTEE EHRLFLLGLQ KVGKGDWRGI  120
SRNFVKTRTP TQVASHAQKY FLRRFNQNRR RRRSSLFDIT TDTFMGSSME EDQAHQETVT  180
LPLPQLQQQQ QQQQQLSRNL GGFPVSTYPL KLAPAVLPVT GSNSMENLTV GPIKQQRTSP  240
KLVRPIPIIP VPPSSKMADL NLNQKGTHVD PLPLSLKLST PSSSSSDEQS PAAQHSSAFQ  300
AMSSGDSSSI ISVA
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor (PubMed:23888064, PubMed:24806884). Direct regulator of the transcription of peroxidase (Prxs) and reactive oxygen species (ROS)-related genes via the recognition of 5'-ATCACA-3' motif (PubMed:24806884). Binds to 5'-TATCCA-3' motif (TA box) and represses the activity of corresponding promoters (e.g. sugar response genes) (PubMed:25920996). Regulates hypocotyl elongation in response to darkness by enhancing auxin accumulation in a phytochrome-interacting factor (PIF) proteins-dependent manner. Promotes lateral roots formation (PubMed:23888064). Promotes cell expansion during leaves development via the modulation of cell wall-located Prxs (PubMed:24806884). Plays a critical role in developmentally regulated and dark-induced onset of leaf senescence by repressing the transcription of several genes involved in chloroplast function and responses to light and auxin. Promotes responses to auxin, abscisic acid (ABA), and ethylene (PubMed:25920996). {ECO:0000269|PubMed:23888064, ECO:0000269|PubMed:24806884, ECO:0000269|PubMed:25920996}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00630PBMTransfer from PK17526.1Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by CdCl(2) (PubMed:16463103). Accumulates in the dark (PubMed:23888064, PubMed:25920996). Diurnal expression pattern with maximal levels in the morning (at protein level). Specifically induced during leaf expansion (PubMed:24806884). Expressed in old and dark-treated leaves (PubMed:25920996). {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:23888064, ECO:0000269|PubMed:24806884, ECO:0000269|PubMed:25920996}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006438524.11e-168transcription factor MYB1R1 isoform X2
SwissprotQ9LVS02e-59KUA1_ARATH; Transcription factor KUA1
TrEMBLA0A2H5N8F01e-167A0A2H5N8F0_CITUN; Uncharacterized protein
STRINGXP_006438522.11e-165(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM97912636
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G70000.22e-77MYB_related family protein
Publications ? help Back to Top
  1. Liu C,Wang B,Li Z,Peng Z,Zhang J
    TsNAC1 Is a Key Transcription Factor in Abiotic Stress Resistance and Growth.
    Plant Physiol., 2018. 176(1): p. 742-756
    [PMID:29122985]