PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

MYB

Protein Properties

Length: 338aa MW: 38263.6 Da PI: 5.413

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_019647-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	60.3	4.2e-19	56	103	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT eEd++l+++++ +G g+W++ ar+ g++Rt+k+c++rw++yl NNU_019647-RA 56 RGPWTVEEDLILINYIANHGEGRWNSLARCAGLKRTGKSCRLRWLNYL 103 89********************************************97 PP
2	Myb_DNA-binding	50.4	5.1e-16	109	152	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg+ T eE++l+++++ ++G++ W++Ia++++ gRt++++k++w++ NNU_019647-RA 109 RGNITLEEQLLILELHSRWGNR-WSKIAQYLP-GRTDNEIKNYWRT 152 7999****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	23.665	51	107	IPR017930	Myb domain
SuperFamily	SSF46689	3.74E-31	53	150	IPR009057	Homeodomain-like
SMART	SM00717	8.8E-16	55	105	IPR001005	SANT/Myb domain
Pfam	PF00249	4.8E-17	56	103	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.9E-23	57	110	IPR009057	Homeodomain-like
CDD	cd00167	1.68E-12	58	103	No hit	No description
SMART	SM00717	2.9E-14	108	156	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	18.378	108	158	IPR017930	Myb domain
Pfam	PF00249	8.6E-15	109	152	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.7E-22	111	157	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009620	Biological Process	response to fungus
GO:0009651	Biological Process	response to salt stress
GO:0009723	Biological Process	response to ethylene
GO:0009737	Biological Process	response to abscisic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 338 aa Download sequence Send to blast
ILRSLLLSIG YRTDTRFPLV FSLSINELFL HFEGMDVNGR GCISGTSSEE EMDLRRGPWT 60 VEEDLILINY IANHGEGRWN SLARCAGLKR TGKSCRLRWL NYLRPDVRRG NITLEEQLLI 120 LELHSRWGNR WSKIAQYLPG RTDNEIKNYW RTRVQKHAKQ LQCDVNSKQF KDTMRYLWMP 180 RLVERIQAAA AASSTANTTT TTTTTTATVA YHPINGDNSD IMASQVPSAG SNNDVGIAQV 240 NTSFTPENSS TAGSSDSIGT QVSPVSDLAD YYTTLQPNSY VDNFQASQVN YQESLTSPTG 300 YFNQGLDFQA IDQNNMWLVD GDTSDNLWNI EDIWFMRQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gv2_A	1e-25	53	156	1	103	MYB PROTO-ONCOGENE PROTEIN
1h8a_C	1e-25	53	150	24	120	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor contributing to the regulation of stamen maturation and male fertility in response to jasmonate signaling. Required for correct timing of anther dehiscence. Acts as a negative regulator of abscisic acid-induced cell death. Not involved in the regulation of BOI. Regulated by MYB21 and at a lower level by MYB24. Negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner. {ECO:0000269\|PubMed:14555693, ECO:0000269\|PubMed:19091873, ECO:0000269\|PubMed:20921156, ECO:0000269\|PubMed:23952703}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00334	DAP	Transfer from AT3G06490	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by jasmonate and pathogen infection. {ECO:0000269\|PubMed:14555693, ECO:0000269\|PubMed:19091873}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010276490.1	0.0	PREDICTED: transcription factor MYB108-like
Swissprot	Q9LDE1	6e-97	MY108_ARATH; Transcription factor MYB108
TrEMBL	A0A1U8B677	0.0	A0A1U8B677_NELNU; transcription factor MYB108-like
STRING	XP_010276490.1	0.0	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G06490.1	2e-96	myb domain protein 108

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Cheng HQ, et al. The cotton MYB108 forms a positive feedback regulation loop with CML11 and participates in the defense response against Verticillium dahliae infection. J. Exp. Bot., 2016. 67(6): p. 1935-50 [PMID:26873979] Sanz-Fernández M, et al. Screening Arabidopsis mutants in genes useful for phytoremediation. J. Hazard. Mater., 2017. 335: p. 143-151 [PMID:28441590] Chou ML, et al. The Direct Involvement of Dark-Induced Tic55 Protein in Chlorophyll Catabolism and Its Indirect Role in the MYB108-NAC Signaling Pathway during Leaf Senescence in Arabidopsis thaliana. Int J Mol Sci, 2018. [PMID:29937503]