PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo

Family

MYB

Protein Properties

Length: 338aa MW: 38962.4 Da PI: 7.8335

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
NNU_003638-RA	genome	CAS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	42.2	1.9e-13	103	139	11	48
HHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 11 llvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +lv++vk++G++ W+ Ia++++ gR +kqc++rw+++l NNU_003638-RA 103 QLVELVKEYGMRKWSQIAQKLN-GRIGKQCRERWHNHL 139 79******************.***********97 PP
2	Myb_DNA-binding	55.4	1.4e-17	145	187	1	45
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 ++ W++eEd +l++++++ G++ W+ Ia++++ gRt++++k++w+ NNU_003638-RA 145 KDTWSEEEDRILIQVHAEIGNK-WAEIAKRLP-GRTENSIKNHWN 187 679*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	4.78E-5	73	127	IPR009057	Homeodomain-like
PROSITE profile	PS51294	18.057	75	139	IPR017930	Myb domain
SMART	SM00717	1.2E-8	79	141	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	4.2E-24	81	146	IPR009057	Homeodomain-like
CDD	cd00167	1.79E-12	83	139	No hit	No description
Pfam	PF00249	1.7E-11	103	139	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	2.16E-27	119	196	IPR009057	Homeodomain-like
PROSITE profile	PS51294	26.498	140	194	IPR017930	Myb domain
SMART	SM00717	2.9E-17	144	192	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-16	145	187	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.0E-22	147	192	IPR009057	Homeodomain-like
CDD	cd00167	6.63E-13	147	190	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010183	Biological Process	pollen tube guidance
GO:0045697	Biological Process	regulation of synergid differentiation
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 338 aa Download sequence Send to blast
MGTLGLLYSP QMTPVVDVME QDTSHPPLNF HEIESSGFEF SDEISCITAN NEFYRKVGLN 60 KRGVSMRKTS KLRTRHNLVK GQWTTEEDRT VDELIMKMCI YRQLVELVKE YGMRKWSQIA 120 QKLNGRIGKQ CRERWHNHLR PNIKKDTWSE EEDRILIQVH AEIGNKWAEI AKRLPGRTEN 180 SIKNHWNATK RRQFSRRRCR SSKCSKSSAS SLLQNYIMSL TAVSTKTDQL HIMLTNSNML 240 PVHTTLRSPT QVESTDSCSA DHLVSDYDFG DTTDFSSGTK LFPERCSIES LLEEMPYASI 300 VDEKSLKMDM PLDMSPLMDG EVIKREMDLV EMITQGNS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1mse_C	3e-43	78	194	2	105	C-Myb DNA-Binding Domain
1msf_C	3e-43	78	194	2	105	C-Myb DNA-Binding Domain
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the motif 5'-GTAACNT-3' in the promoter of target genes (e.g. DD11 and DD18) and promotes their expression within synergid cells (e.g. in the filiform apparatus) in ovules (PubMed:16214903, PubMed:17693534, PubMed:18410484, PubMed:17937500). Required for the formation of the filiform apparatus during synergid cell differentiation in the female gametophyte (PubMed:16214903). Involved in pollen tube guidance to the micropyle (PubMed:16214903, PubMed:17937500, PubMed:23093426). {ECO:0000269\|PubMed:16214903, ECO:0000269\|PubMed:17693534, ECO:0000269\|PubMed:17937500, ECO:0000269\|PubMed:18410484, ECO:0000269\|PubMed:23093426}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00442	DAP	Transfer from AT4G18770	Download

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010250365.1	0.0	PREDICTED: transcription factor MYB98-like
Swissprot	Q9S7L2	4e-75	MYB98_ARATH; Transcription factor MYB98
TrEMBL	A0A1U7ZA48	0.0	A0A1U7ZA48_NELNU; transcription factor MYB98-like
STRING	XP_010250365.1	0.0	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18770.1	8e-66	myb domain protein 98

Publications ? help Back to Top
Mendes MA, et al. Live and let die: a REM complex promotes fertilization through synergid cell death in Arabidopsis. Development, 2016. 143(15): p. 2780-90 [PMID:27338615]