PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.N03347.1.p
Common NameMIMGU_mgv1a021980mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family NAC
Protein Properties Length: 342aa    MW: 39154.4 Da    PI: 5.8967
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.N03347.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM168.13e-5281381128
               NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvka....eekewyfFskrdkkyatgkrknratksgyWkatgkd 89 
                       +ppGfrF+Pt+eelv +yL +kv++ k++l +vi ++d+y++ePwd+++++k+    e++ewyfFs++d+ky+tg+r+nrat++g+Wkatg+d
  Migut.N03347.1.p   8 VPPGFRFRPTEEELVGYYLSRKVNSLKIDL-DVIIDIDLYRIEPWDIQERCKSgsvsEQNEWYFFSHKDRKYPTGTRTNRATAAGFWKATGRD 99 
                       69****************************.99**************9644443454778********************************* PP

               NAM  90 kevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                       k+v+sk+++l+g++ktLv+y+grap+g+k+dW+mheyr+
  Migut.N03347.1.p 100 KAVHSKEDKLIGMRKTLVYYEGRAPNGRKSDWIMHEYRI 138
                       *************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019413.01E-575159IPR003441NAC domain
PROSITE profilePS5100556.5968159IPR003441NAC domain
PfamPF023652.2E-279138IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 342 aa     Download sequence    Send to blast
MEYSSTSVPP GFRFRPTEEE LVGYYLSRKV NSLKIDLDVI IDIDLYRIEP WDIQERCKSG  60
SVSEQNEWYF FSHKDRKYPT GTRTNRATAA GFWKATGRDK AVHSKEDKLI GMRKTLVYYE  120
GRAPNGRKSD WIMHEYRIQA SEHEPTQEEG WVVCRAFKKP SPSHKQGFEA WNNNTNYYAI  180
RSSSSDITNY RHPSSFPSNT STNLLIHKDD ILDDLGLISN QSGASNSCTP VNINQPPLTI  240
FPVDQSDNDL KTGFISRLEI SQMVELPKLD SPSDDKISSF GDMSYSEWKS FDKLHYSTCT  300
QVEEINAASS SYAYTNMHDN YHDLLDDHTH ISNVLECFPH L*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A3e-47416513171NO APICAL MERISTEM PROTEIN
1ut4_B3e-47416513171NO APICAL MERISTEM PROTEIN
1ut7_A3e-47416513171NO APICAL MERISTEM PROTEIN
1ut7_B3e-47416513171NO APICAL MERISTEM PROTEIN
3swm_A3e-47416516174NAC domain-containing protein 19
3swm_B3e-47416516174NAC domain-containing protein 19
3swm_C3e-47416516174NAC domain-containing protein 19
3swm_D3e-47416516174NAC domain-containing protein 19
3swp_A3e-47416516174NAC domain-containing protein 19
3swp_B3e-47416516174NAC domain-containing protein 19
3swp_C3e-47416516174NAC domain-containing protein 19
3swp_D3e-47416516174NAC domain-containing protein 19
4dul_A3e-47416513171NAC domain-containing protein 19
4dul_B3e-47416513171NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.N03347.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012853347.10.0PREDICTED: NAC domain-containing protein 76-like
SwissprotQ9C8W92e-95NAC30_ARATH; NAC domain-containing protein 30
TrEMBLA0A022Q5N40.0A0A022Q5N4_ERYGU; Uncharacterized protein
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G71930.19e-79vascular related NAC-domain protein 7
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  3. Li Z, et al.
    A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis.
    Plant Physiol., 2016. 172(2): p. 1334-1351
    [PMID:27566165]
  4. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  5. Tan TT, et al.
    Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation.
    Plant Physiol., 2018. 176(1): p. 773-789
    [PMID:29133368]
  6. Ohashi-Ito K,Iwamoto K,Fukuda H
    LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements.
    Plant Cell Physiol., 2018. 59(5): p. 989-996
    [PMID:29444288]