PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

bHLH

Protein Properties

Length: 261aa MW: 29331.1 Da PI: 7.6503

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.N02717.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26	1.7e-08	163	203	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Migut.N02717.1.p 163 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 203 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.218	154	203	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.6E-13	159	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.62E-14	159	213	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.3E-14	160	209	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	7.7E-6	164	203	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.53E-6	177	208	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0048462	Biological Process	carpel formation
GO:0080126	Biological Process	ovary septum development
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 261 aa Download sequence Send to blast
MDIEFMKSAA EDQMEMMLMQ MDKLPDFSTA TYDHHNIPLM DEFTNNNNTV LENPTFMNHH 60 HHHHHPSSTI SFSGGVHHEP PSFLQHPPPN TSGGRWQTNE YYDDHSGSGG GAAAQKRHSN 120 MAAMREMIFR IAAMQPIHID PESVKPPKRR NVKISTDPQS VAARHRRERI SERIRILQRL 180 VPGGTKMDTA SMLDEAIHYV KFLKNQVQSL ERVSANRPSA AAPDGIGFPV PMLSGNYFPA 240 GMNNMKGYRQ SSPPNVQMLE *

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.N02717.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP257546	7e-99	KP257546.1 Salvia miltiorrhiza clone 114 basic helix-loop-helix transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012838731.1	1e-164	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	6e-47	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A022R7T1	0.0	A0A022R7T1_ERYGU; Uncharacterized protein

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	7e-42	bHLH family protein

Link Out ? help Back to Top
Phytozome	Migut.N02717.1.p

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]