PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

WRKY

Protein Properties

Length: 503aa MW: 55232.9 Da PI: 8.2419

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.L01234.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	107.8	5.2e-34	229	285	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 dDgynWrKYGqK+vkgse+prsYY+Ct+++Cpvkkkvers d +++ei+Y+g+Hnh+ Migut.L01234.1.p 229 DDGYNWRKYGQKQVKGSEYPRSYYKCTHPKCPVKKKVERSL-DAQITEIIYKGQHNHP 285 8**************************************.*************8 PP
2	WRKY	107.1	8.9e-34	383	441	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDgy+WrKYGqK+vkg+++prsYY+Cts+gC+v+k+ver+a+dpk+v++tYeg+Hnh+ Migut.L01234.1.p 383 LDDGYRWRKYGQKVVKGNPYPRSYYKCTSQGCNVRKHVERAATDPKAVITTYEGKHNHD 441 59********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.2E-31	222	287	IPR003657	WRKY domain
SuperFamily	SSF118290	1.83E-26	226	287	IPR003657	WRKY domain
SMART	SM00774	4.9E-38	228	286	IPR003657	WRKY domain
Pfam	PF03106	4.5E-26	229	285	IPR003657	WRKY domain
PROSITE profile	PS50811	24.202	229	287	IPR003657	WRKY domain
Gene3D	G3DSA:2.20.25.80	1.3E-37	368	443	IPR003657	WRKY domain
SuperFamily	SSF118290	7.45E-30	375	443	IPR003657	WRKY domain
PROSITE profile	PS50811	39.157	378	443	IPR003657	WRKY domain
SMART	SM00774	5.7E-40	383	442	IPR003657	WRKY domain
Pfam	PF03106	2.6E-26	384	441	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 503 aa Download sequence Send to blast
MAENEFQPPR RPQPTSRPPA PTITLPPRSA VDSLFMGVGA AAGVSPGPMS LVSSFFAEND 60 DPDNDCRSFS QLLAGAISSP PSAANVRHNF GQPAAENRGG DGGSGEFRFQ QNRPAGLMVS 120 QQHGMFTIPA GLSPASLLDS PVFFPSSQGA MGTSHQHFLA QLTAQAQMNI HSSYPSSSSA 180 SLPPHYSNAT LQINSLPGRN IVKESSDISN SDQKLQLAAP NLVVDKPADD GYNWRKYGQK 240 QVKGSEYPRS YYKCTHPKCP VKKKVERSLD AQITEIIYKG QHNHPPPAKR TKDYPDGGIN 300 HHGNSELDSR TTNEGIKDQE SSQFTHERVT GSSDSDEVNG SHEDEPESKR RNIEVQTTEQ 360 ASSHRTVTEP RIIVQTTSEV DLLDDGYRWR KYGQKVVKGN PYPRSYYKCT SQGCNVRKHV 420 ERAATDPKAV ITTYEGKHNH DVPAAKNSSH STANNAAASS SSQSRPQNAS FDRQMENRRI 480 EFRSNEMQHP VSLLRFKEEH IT*

Sequence ? help Back to Top

Protein Sequence Length: 503 aa Download sequence Send to blast

MAENEFQPPR RPQPTSRPPA PTITLPPRSA VDSLFMGVGA AAGVSPGPMS LVSSFFAEND  60
DPDNDCRSFS QLLAGAISSP PSAANVRHNF GQPAAENRGG DGGSGEFRFQ QNRPAGLMVS  120
QQHGMFTIPA GLSPASLLDS PVFFPSSQGA MGTSHQHFLA QLTAQAQMNI HSSYPSSSSA  180
SLPPHYSNAT LQINSLPGRN IVKESSDISN SDQKLQLAAP NLVVDKPADD GYNWRKYGQK  240
QVKGSEYPRS YYKCTHPKCP VKKKVERSLD AQITEIIYKG QHNHPPPAKR TKDYPDGGIN  300
HHGNSELDSR TTNEGIKDQE SSQFTHERVT GSSDSDEVNG SHEDEPESKR RNIEVQTTEQ  360
ASSHRTVTEP RIIVQTTSEV DLLDDGYRWR KYGQKVVKGN PYPRSYYKCT SQGCNVRKHV  420
ERAATDPKAV ITTYEGKHNH DVPAAKNSSH STANNAAASS SSQSRPQNAS FDRQMENRRI  480
EFRSNEMQHP VSLLRFKEEH IT*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-42	229	444	8	78	Probable WRKY transcription factor 4
2lex_A	1e-42	229	444	8	78	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00260	DAP	Transfer from AT2G03340	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.L01234.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid and during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012847588.1	0.0	PREDICTED: probable WRKY transcription factor 3
Swissprot	Q9ZQ70	1e-151	WRKY3_ARATH; Probable WRKY transcription factor 3
TrEMBL	A0A022QQN5	0.0	A0A022QQN5_ERYGU; Uncharacterized protein
STRING	Migut.L01234.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4107	24	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G13960.1	1e-135	WRKY DNA-binding protein 4

Link Out ? help Back to Top
Phytozome	Migut.L01234.1.p
Entrez Gene	105967534

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Aamir M, et al. Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach. Front Plant Sci, 2017. 8: p. 819 [PMID:28611792]