PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

NAC

Protein Properties

Length: 293aa MW: 33687.6 Da PI: 6.6325

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.L00568.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	162.7	1.4e-50	10	134	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 lp+GfrFhPtdeelvv+yL+++++g+++ +i+e+d+yk++Pw+Lp + +ekewyfFs+rd+ky++g+r+nra+ +gyWkatg dk+v Migut.L00568.1.p 10 LPAGFRFHPTDEELVVHYLCRRCAGHQIAP-PIIAEIDLYKFDPWQLPGMSLYGEKEWYFFSPRDRKYPNGSRPNRAAGAGYWKATGADKPVG 101 799**********************988.78***********65556799********************************9 PP NAM 94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128 + ++ g+kk Lvfy g+apkg kt+W+mheyrl Migut.L00568.1.p 102 K--PKTLGIKKALVFYAGKAPKGIKTNWIMHEYRL 134 8..778*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	4.71E-61	7	160	IPR003441	NAC domain
PROSITE profile	PS51005	59.513	10	160	IPR003441	NAC domain
Pfam	PF02365	9.7E-27	11	134	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0008361	Biological Process	regulation of cell size
GO:0009416	Biological Process	response to light stimulus
GO:0009611	Biological Process	response to wounding
GO:0009620	Biological Process	response to fungus
GO:0009744	Biological Process	response to sucrose
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0043424	Molecular Function	protein histidine kinase binding

Sequence ? help Back to Top
Protein Sequence Length: 293 aa Download sequence Send to blast
MKGGDQQLSL PAGFRFHPTD EELVVHYLCR RCAGHQIAPP IIAEIDLYKF DPWQLPGMSL 60 YGEKEWYFFS PRDRKYPNGS RPNRAAGAGY WKATGADKPV GKPKTLGIKK ALVFYAGKAP 120 KGIKTNWIMH EYRLANVDRS AGKTNNLRLD DWVLCRIYNK KGTLEKHYNV VDQEAVQFSD 180 NEEQKPNVNT NVFPRNNNPM NNEYVNFDTS DSTPKLNNTY SSTTSSHEHV LSPDFKEVQS 240 EPKWSEFESN TPFGFQTNYY MDDVFQEDPF AYQTMQYNNE QLSLLQEVFG YN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	4e-81	2	166	7	174	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Involved in disease resistance response (PubMed:16115070, PubMed:19625399). May function as repressor of pathogenesis-related proteins (PubMed:16115070). May function in the regulation of host basal defense responses against viral infection (PubMed:19625399). Transcriptional activator involved in responses to wounding and infection with tobamovirus (TMV) (PubMed:22937923). Binds to the DNA sequences 5'-AAAATATCT-3' and 5'AGATTTTT-3' of CYP734A1/BAS1 and CYP72C1/SOB7 promoters, respectively. Acts as suppressor of the brassinosteroid (BR)-inactivating enzymes CYP734A1/BAS1 and CYP72C1/SOB7, and prevents their expression in almost all tissues. Plays a central role in integrating BR homeostasis and seedling development. Regulates the spatial regulation of BR homeostasis and participates in the regulation of hypocotyl elongation and root growth by suppressing BR catabolism. Mediates connection between BR catabolism and photomorphogenesis (PubMed:26493403). Binds to, and transactivates the promoter of the auxin biosynthetic gene NIT2 (PubMed:22965747). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:18849494, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22937923, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403, ECO:0000269\|PubMed:26518251}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.L00568.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding, salicylic acid (SA), methyl jasmonate, drought stress, dark and sucrose starvation (PubMed:16115070). Induced by chitin elicitor (chitooctaose) (PubMed:17722694). Induced by salicylic acid and infection with tobamovirus (TMV) (PubMed:19625399). By indole-3-acetonitrile, salicylic acid (SA), sodium nitroprusside (SNP), salt stress and drought stress (PubMed:22965747). Down-regulated by brassinosteroid (BR) and transition from dark to white light (PubMed:26493403). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:17722694, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012829076.1	0.0	PREDICTED: protein ATAF2-like
Swissprot	Q9C598	1e-120	NAC81_ARATH; Protein ATAF2
TrEMBL	A0A022PST5	0.0	A0A022PST5_ERYGU; Uncharacterized protein
STRING	Migut.L00568.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1239	24	81

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08790.1	1e-120	NAC family protein

Link Out ? help Back to Top
Phytozome	Migut.L00568.1.p

Publications ? help Back to Top
Takasaki H, et al. SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence. Plant J., 2015. 84(6): p. 1114-23 [PMID:26518251]