PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.I00613.1.p
Common NameLOC105975799, MIMGU_mgv1a001371mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family ARF
Protein Properties Length: 833aa    MW: 92564 Da    PI: 6.344
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.I00613.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.99.4e-24143244199
                       EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS CS
                B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgr 87 
                       f+k+lt sd++++g +++ +++a+e+      + + + +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + 
  Migut.I00613.1.p 143 FCKTLTASDTSTHGGFSVLRRHADEClppldmSRQ-PPTQELVAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RG 232
                       99*****************************7333.34459************************************************..44 PP

                       SEE..EEEEE-S CS
                B3  88 sefelvvkvfrk 99 
                       +++el+v+v+r+
  Migut.I00613.1.p 233 ENGELRVGVRRA 244
                       9999*****996 PP
2Auxin_resp119.82.1e-39269351183
        Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                       a+ha++tk++F+v+Y+Pr+s++eF+v+++++++++k+++s+GmRfkm+fe+e+++e+r++Gt+vg++d+d+ rWp+SkWr+Lk
  Migut.I00613.1.p 269 AWHAIQTKTMFTVYYKPRTSPAEFIVSYDQYMESVKNNYSIGMRFKMRFEGEEAPEQRFTGTIVGTEDADSKRWPESKWRCLK 351
                       89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.7E-40139272IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.9E-41140258IPR015300DNA-binding pseudobarrel domain
CDDcd100177.42E-22141243No hitNo description
SMARTSM010192.0E-23143245IPR003340B3 DNA binding domain
PfamPF023621.1E-21143244IPR003340B3 DNA binding domain
PROSITE profilePS5086312.012143245IPR003340B3 DNA binding domain
PfamPF065076.5E-37269351IPR010525Auxin response factor
PROSITE profilePS5174522.545705787IPR000270PB1 domain
SuperFamilySSF542779.22E-11706782No hitNo description
PfamPF023091.3E-6751795IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009734Biological Processauxin-activated signaling pathway
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 833 aa     Download sequence    Send to blast
MAASEVSIKG YSDANDCNSG TDKANSGAGK VDTETALYTE LWRACAGPLV TVPRENELVF  60
YFPQGHMEQV EASTNQSADQ QMPVYNLPPK ILCRVVNVNL KAEPDTDEVF AQVTLMPEPN  120
QDENAAKKEP LPSPPPCFHV HSFCKTLTAS DTSTHGGFSV LRRHADECLP PLDMSRQPPT  180
QELVAKDLHG NEWRFRHIFR GQPRRHLLQS GWSVFVSSKR LVAGDAFIFL RGENGELRVG  240
VRRAMRQQGN APSSVISSHS MHLGVLATAW HAIQTKTMFT VYYKPRTSPA EFIVSYDQYM  300
ESVKNNYSIG MRFKMRFEGE EAPEQRFTGT IVGTEDADSK RWPESKWRCL KVRWDETSTI  360
PRPERVSPWK IEPALSPPAL NPLPVPRPKR PRSSVLPSSP DSSVLTREGP SKMTVDPSPA  420
NGFQRVLQGQ ELSTLRGTFA ESNESEASEK PLLWNPSLDE DKIDALSASK RYMPDKWLPI  480
GRPESSFTDL LSGFGSQISG SRDFCMPPGD EAVSKRQRQD QQHEAKFSFI GNNNNWSIMP  540
SGLSLNLMDS SQGQGTTDVR YGGGFREYSL MPDSRGGDNQ QRNWLMPPPI SPYLQMGPAQ  600
PRELMPKSAF MQQQPSHDSM KPKEGNCKLF GIPLRSSSNS ASLDQTLSQR TAMIERASHM  660
QLGLHSHQSP AIESDQSKGS KMVDSPVATS EQDKPVTKVH SGSTRSCTKV HKQGTALGRS  720
VDLAKFDNYD ELIAELDNLF EFNGELKAKT KNWLVVYTDD EDDMMLVGDD PWDEFCGMVR  780
KILILTKEEV QRMSPGTFNS KGEEMSSVAE GLDAKEVKNL PATTSSSSPD NC*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1783637318354Auxin response factor 1
4ldw_A1e-1783637318354Auxin response factor 1
4ldw_B1e-1783637318354Auxin response factor 1
4ldx_A1e-1773637318354Auxin response factor 1
4ldx_B1e-1773637318354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor (PubMed:26959229, PubMed:26716451, PubMed:27645097, PubMed:28167023). Involved in the control of fruit ripening process (PubMed:26959229, PubMed:26716451, PubMed:28167023). Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26959229, PubMed:26716451). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). Regulates vegetative growth, lateral root formation and flower organ senescence, possibly partially by regulating gene expression of auxin and ethylene response factor (ERF) genes (PubMed:28167023). Plays a negative role in axillary shoot meristem formation (PubMed:27645097). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.I00613.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression in tomato fruits is up-regulated by exogenous application of ethylene and down-regulated by inhibition of ethylene receptors with 1-methylcyclopropene (1-MCP) (PubMed:26959229, PubMed:26716451). Up-regulated by plant hormone abscisic acid (ABA) in tomato fruits (PubMed:26959229). Expression is not up-regulated by plant hormone auxin in tomato fruits (PubMed:26716451). Up-regulated by auxin and gibberellic acid (GA), and down-regulated by ethylene in seedlings (PubMed:28167023). Down-regulated during decapitation-induced axillary shoot development and by excision of immature leaves. Down-regulation is inhibited by the application of auxin on the cut surface (PubMed:27645097). {ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012856487.10.0PREDICTED: auxin response factor 2
SwissprotQ2LAJ30.0ARF2A_SOLLC; Auxin response factor 2A
TrEMBLA0A022Q1X60.0A0A022Q1X6_ERYGU; Auxin response factor
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA26182444
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]
  3. Xu T, et al.
    SlARF2a plays a negative role in mediating axillary shoot formation.
    Sci Rep, 2016. 6: p. 33728
    [PMID:27645097]
  4. Ren Z,Liu R,Gu W,Dong X
    The Solanum lycopersicum auxin response factor SlARF2 participates in regulating lateral root formation and flower organ senescence.
    Plant Sci., 2017. 256: p. 103-111
    [PMID:28167023]