PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr8g104930.1

Common Name

MTR_8g104930

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

C2H2

Protein Properties

Length: 464aa MW: 51578 Da PI: 7.2803

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr8g104930.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14	0.00015	109	131	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+Cp+C+++F++ ++ + H ++ Medtr8g104930.1 109 YECPICKQPFRSEDEVTEHVESC 131 99*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF143503	1.12E-18	170	255	IPR018997	PUB domain
CDD	cd09212	8.76E-21	174	258	No hit	No description
Pfam	PF09409	7.3E-17	176	248	IPR018997	PUB domain
SMART	SM00580	1.2E-20	176	243	IPR018997	PUB domain
SuperFamily	SSF54236	9.04E-13	323	436	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	1.8E-8	351	436	No hit	No description
PROSITE profile	PS50033	9.898	352	436	IPR001012	UBX domain
Pfam	PF00789	1.2E-4	354	402	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 464 aa Download sequence Send to blast
MDDVKDKMKG FIKKVNNPFT SSSSGKFKGQ GRVLGSSSSS STPANSIPTP THRPSPSQNP 60 NPKPKPTPPI ASDQSKIDKP RKPADGFDPF DSLVTSSQRS QNGYSLNVYE CPICKQPFRS 120 EDEVTEHVES CLSNPIENDD VDEKCVSKLK ESQVSESNTE LEICIGTYVS GNPSQGSVDI 180 VLKLLRNIVK EPDNVKFRKI RMGNPKIKEA IGEVIGGVEL LSLLGFELKE ENGETWALME 240 VPTEEKVNLI KKAIVLLEPQ LVQDTPKREN STPTVSTEKV AEAEPKKIDR QVKVFFAVSE 300 SVAARIELPD SFYKRSAEEV RREAELRRKK IEESQLLIPK SLKEKQAKAA KRRYTRTIIR 360 IQFPDGVVLQ GVFAPWEPTT ALYEFVSSAL KESCLEFELM HPVVVQRRVI PCFPKAGQKA 420 KTIEEEDLVP SALIKFKPLE TDSVVFTGLK NELLEISEPL VNG*

Sequence ? help Back to Top

Protein Sequence Length: 464 aa Download sequence Send to blast

MDDVKDKMKG FIKKVNNPFT SSSSGKFKGQ GRVLGSSSSS STPANSIPTP THRPSPSQNP  60
NPKPKPTPPI ASDQSKIDKP RKPADGFDPF DSLVTSSQRS QNGYSLNVYE CPICKQPFRS  120
EDEVTEHVES CLSNPIENDD VDEKCVSKLK ESQVSESNTE LEICIGTYVS GNPSQGSVDI  180
VLKLLRNIVK EPDNVKFRKI RMGNPKIKEA IGEVIGGVEL LSLLGFELKE ENGETWALME  240
VPTEEKVNLI KKAIVLLEPQ LVQDTPKREN STPTVSTEKV AEAEPKKIDR QVKVFFAVSE  300
SVAARIELPD SFYKRSAEEV RREAELRRKK IEESQLLIPK SLKEKQAKAA KRRYTRTIIR  360
IQFPDGVVLQ GVFAPWEPTT ALYEFVSSAL KESCLEFELM HPVVVQRRVI PCFPKAGQKA  420
KTIEEEDLVP SALIKFKPLE TDSVVFTGLK NELLEISEPL VNG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	3e-12	307	436	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.15762	0.0	root\| stem

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr8g104930.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC150979	0.0	AC150979.15 Medicago truncatula clone mth2-115a17, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003630914.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	G7LAI2	0.0	G7LAI2_MEDTR; Plant UBX domain protein
STRING	AET05390	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8944	25	29

Link Out ? help Back to Top
Phytozome	Medtr8g104930.1
Entrez Gene	11412894

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]