PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr8g089895.1
Common NameMTR_8g089895
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family HD-ZIP
Protein Properties Length: 312aa    MW: 35261 Da    PI: 4.3325
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr8g089895.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.51.1e-1854107356
                      --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
         Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                      k+++++ +q+++Le+ Fe ++++  +++ +LA++lgL+ rqV vWFqNrRa++k
  Medtr8g089895.1  54 KKRRLSVDQVKALEKNFEVENKLEPDRKVKLAQELGLQPRQVAVWFQNRRARWK 107
                      456899***********************************************9 PP
2HD-ZIP_I/II128.23.4e-4153145193
      HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 
                      +kkrrls +qvk+LE++Fe e+kLep+rKv+la+eLglqprqvavWFqnrRAR+ktkqlE+dy +Lk++ydalk + e L++++e+L +e+ke
  Medtr8g089895.1  53 QKKRRLSVDQVKALEKNFEVENKLEPDRKVKLAQELGLQPRQVAVWFQNRRARWKTKQLERDYGVLKANYDALKLNCEDLQRDKETLLKEVKE 145
                      69**************************************************************************************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466894.28E-1948111IPR009057Homeodomain-like
PROSITE profilePS5007117.4149109IPR001356Homeobox domain
SMARTSM003893.9E-1852113IPR001356Homeobox domain
CDDcd000863.08E-1653110No hitNo description
PfamPF000468.3E-1654107IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.607.9E-2056116IPR009057Homeodomain-like
PRINTSPR000318.7E-68089IPR000047Helix-turn-helix motif
PROSITE patternPS00027084107IPR017970Homeobox, conserved site
PRINTSPR000318.7E-689105IPR000047Helix-turn-helix motif
PfamPF021835.0E-16109151IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 312 aa     Download sequence    Send to blast
MKRLGSSDSL GALMTICPTT EEESPRNNQV YGREFQSMME GLDEEGCVDE PGQKKRRLSV  60
DQVKALEKNF EVENKLEPDR KVKLAQELGL QPRQVAVWFQ NRRARWKTKQ LERDYGVLKA  120
NYDALKLNCE DLQRDKETLL KEVKELKSRL QIQEENTTTE SDVCVKEELI TLQESENTAS  180
DETAILRSDS KDLNNDCFKN GDGVASLFPA DFKDGSSDSD SSAILNEESN AAISSSGVLQ  240
NHNFLMSPGS SSLKFNCSES SSPSSMSNCF QFQTQFVKME EHNFLSADET CDFFSDEQPP  300
TLQWYCSEEW N*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1101109RRARWKTKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.140330.0flower| leaf| pod| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:16055682}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'-CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00271DAPTransfer from AT2G22430Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr8g089895.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. Self expression regulation. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416, ECO:0000269|PubMed:16055682}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0507890.0BT050789.1 Medicago truncatula clone MTYF5_F6_F7_F81G-J-3 unknown mRNA.
GenBankBT1337230.0BT133723.1 Medicago truncatula clone JCVI-FLMt-17N17 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013446755.10.0homeobox-leucine zipper protein ATHB-6
SwissprotP466682e-80ATHB6_ARATH; Homeobox-leucine zipper protein ATHB-6
TrEMBLA0A072TTL60.0A0A072TTL6_MEDTR; Homeobox associated leucine zipper protein
STRINGXP_004504111.11e-167(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18683489
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22430.19e-76homeobox protein 6
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]