PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr8g027495.1
Common NameMTR_8g027495
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family bHLH
Protein Properties Length: 624aa    MW: 68870.1 Da    PI: 7.5617
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr8g027495.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.45.2e-13458504455
                      HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
              HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                      +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Medtr8g027495.1 458 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 504
                      799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.7E-5353241IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.837454503IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.13E-18457520IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.22E-15457508No hitNo description
Gene3DG3DSA:4.10.280.101.2E-18458517IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10458504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.2E-17460509IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 624 aa     Download sequence    Send to blast
MKIEVGLGGN RLWNEDEKAM VVEVLGVNAF DYLVTNSVSN ENLLTAIGSG ENLENKLSDL  60
VERSNVSNFS WNYAIFWRIS QSKFGDWVLG WGDGCCREPK EEEKEQNLGL KSVVEDEKQQ  120
RMRKRVLQKL HATFGGLDDD NYAFGLDCVT DTEMFFLASM YFSFPNGHGG PGKCFASGKH  180
LWLCDALKSS SSDYCVRAFL AKSVGFKTIV LVPTDLGVVE LGSVRTVGES VELLQTIKSV  240
FSTQSSFARA KSISSLDGKR DENSPFSCLK VGESVKNNSN NNGNLHLHHQ NNNNHGRVEG  300
IGVPKIFGQD LNSATHFREK LAIRKMDDRQ SWGGRPNGNG ISFPNGVHGS SWRGSQVVRQ  360
HAPVDVFAPR PSSSNAAELA NGGRQDFVLN NYQQQRKPQM QIDFSGATSR PSVRSIVGES  420
ELSDVEASCR EENPSPSDDR RPRKRGRKPA NGRVEPLNHV EAERQRREKL NQRFYALRAV  480
VPNISKMDKA SLLGDAIAYI NELQAKLKTM ESEREQLGIT SRDGSSSAPP ANSRAENPQS  540
RAPDIDIQAA QDGVIVKVSC SIDVHPISKV IQSFKDTEID IVESKLNAAN DTVFHTFIIK  600
SQGSEQLTKE KLIAAFSKET NSL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-29452517267Transcription factor MYC2
5gnj_B1e-29452517267Transcription factor MYC2
5gnj_E1e-29452517267Transcription factor MYC2
5gnj_F1e-29452517267Transcription factor MYC2
5gnj_G1e-29452517267Transcription factor MYC2
5gnj_I1e-29452517267Transcription factor MYC2
5gnj_M1e-29452517267Transcription factor MYC2
5gnj_N1e-29452517267Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1439447RRPRKRGRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.99490.0leaf| root| seed
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr8g027495.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013444608.10.0transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A072TP530.0A0A072TP53_MEDTR; ABA-inducible bHLH-type transcription factor
STRINGXP_004510665.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-171bHLH family protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  3. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  4. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]